The effects of zilpaterol hydrochloride on carcass cutability and tenderness of calf-fed Holstein steers.

To evaluate the impact of zilpaterol hydrochloride (ZH) on carcass cutability and tenderness of calf-fed Holstein steers, calf-fed Holstein carcasses (n = 102) were selected from a pool of 2,300 steers that were fed 0 or 8.3 mg/kg (DM basis) of ZH. Zilpaterol hydrochloride was supplemented the last 20 d of the finishing period and withdrawn for 3 d before slaughter. Carcasses were selected based on carcass weight as well as predetermined USDA Yield grade categories. For tenderness evaluation, steaks from the strip loin, bottom round, and top round (n = 54 per subprimal) were aged for 14 or 21 d postmortem. Carcasses from ZH-fed steers had more (P < 0.01) saleable yield than carcasses from control-fed steers. Additionally, ZH-fed steers had greater (P < or = 0.01) subprimal yield from the shoulder clod, strip loin, peeled tenderloin, top sirloin butt, bottom sirloin tri-tip, peeled knuckle, inside round, bottom round flat, eye of round, heel, and shank. Furthermore, ZH decreased (P < 0.01) the total amount and percentage of bone and fat trim from the carcass. Moisture loss was not affected by ZH in LM or inside round steaks (P > 0.05); however, ZH increased thawing loss (P = 0.05) but reduced cooking loss (P = 0.05) in bottom round steaks. Shear force values of LM and inside round steaks increased with ZH inclusion (P < 0.01), but there was no difference in bottom round steaks (P > 0.05). Steaks aged for 21 d had smaller (P < 0.01) Warner-Bratzler shear force (WBS) values than 14-d steaks from all 3 subprimals. Trained sensory panelists did not detect any differences (P > 0.05) in sensory juiciness, tenderness, or flavor variables of LM or inside round steaks, except ZH steaks from the LM received smaller scores for sustained juiciness (P = 0.01) and overall tenderness (P = 0.04) than control steaks. Although LM steaks from ZH cattle were tougher than control steaks, the ZH-treated steaks had an average WBS value of 4.10 kg, which would be classified as intermediate in tenderness, with trained panelists rating ZH steaks slightly to moderately tender. Feeding ZH improved carcass cutability of calf-fed Holstein steers; however, tenderness was reduced in LM and inside round steaks. The interaction of postmortem tenderization techniques should be investigated to evaluate their impact on palatability in cattle supplemented with beta-agonists to allow the beef industry to take full advantage of the enhancement in performance and carcass yield.

Effect of bovine respiratory disease during preconditioning on subsequent feedlot performance, carcass characteristics, and beef attributes.

Heifers with expected increased risk of bovine respiratory disease (BRD; n = 360; initial BW = 241.3 +/- 16.6 kg) were assembled at a Kentucky order-buyer facility and delivered to Stillwater, OK, in September 2007 to determine the effects of clinical BRD observed during preconditioning on subsequent feedlot performance, carcass characteristics, and meat attributes. During a 63-d preconditioning period, morbidity and mortality attributed to BRD were 57.6 and 8.6%, respectively. Immediately after preconditioning, heifers were grouped according to health outcome category and allotted to finishing pens (5 to 7 heifers/pen). Heifers were never treated for BRD (0X; n = 9 pens), treated 1 time (1X; n = 9 pens), 2 times (2X; n = 6 pens), 3 times (3X; n = 6 pens), or designated as chronically ill (CI; n = 2 pens). Arrival BW was not different (P = 0.21) among treatment categories. However, disease incidence during preconditioning decreased (P < 0.001) growth, resulting in BW of 318, 305, 294, 273, and 243 kg for 0X, 1X, 2X, 3X, and CI, respectively, at the start of the finishing phase. Estimates on the LM, taken by ultrasound on d 65 and 122, were combined with BW and visual appraisal to target common average endpoint within category and block. On average, heifers were slaughtered on d 163 for 0X, 1X, and 2X, d 182 for 3X, and d 189 for CI (P < 0.01). Final BW was similar (P > or = 0.18) for heifers treated 0, 1, 2, or 3 times, but heifers deemed CI weighed less (P = 0.01) than 3X heifers. Considering the finishing phase only, ADG was linearly increased (P < 0.001) with increasing BRD treatments, but was linearly decreased (P = 0.003) as BRD treatments increased from arrival to slaughter. Therefore, G:F was greater (P = 0.007) for CI than 3X and linearly increased (P = 0.002) from 0X to 3X. Similar to BW, HCW was less (P = 0.03) for CI than 3X. Marbling score tended (P = 0.06) to decrease linearly as the number of treatments increased, but no other differences (P > or = 0.24) in carcass traits were detected. No differences were observed in beef tenderness (P = 0.65), and no consistent trends were noted in retail display or palatability data. Less than 20 additional days on feed were required for heifers treated 3 times to have similar BW and carcass characteristics to heifers never treated for BRD. Segregating animals with multiple BRD treatments and feeding them to an acceptable carcass endpoint may be a viable strategy for increasing value of animals treated for BRD.

Effect of extended withdrawal of zilpaterol hydrochloride on performance and carcass traits in finishing beef steers.

The objective was to evaluate the effects of an extended withdrawal period after feeding the beta-adrenergic agonist zilpaterol hydrochloride (ZH) for 20 d at the end of the feeding period. Three hundred eighty-four crossbred beef steers were blocked by BW and randomly allocated into 64 pens (6 steers/pen). Pens were assigned to treatments in a 2 x 4 factorial arrangement in a randomized complete block design. Main effects were the addition of 0 (control) or 8.3 mg/kg of ZH (DM basis) to the finishing diet for 20 d before estimated average slaughter date and paired withdrawal periods of 3, 10, 17, or 24 d before slaughter. Individual BW were measured initially, 1 d before ZH feeding, and 1 d before slaughter. The ZH feeding period was initiated so that control cattle in the 3-d withdrawal group would be expected to average 65% USDA Choice Quality grade and have 1.27 cm of 12th-rib fat based on visual appraisal. Carcass data were collected at slaughter. For the 3-d withdrawal steers, 2 steers from each pen were selected to determine visceral organ and total offal mass at slaughter. The ZH x withdrawal day interaction was not significant (P > 0.10) for the majority of variables. There was no difference (P > or = 0.12) due to ZH feeding for final BW, carcass-adjusted final BW, or ADG. However, DMI was decreased (P = 0.02) and G:F increased (P = 0.01) in steers fed ZH vs. control steers. As day after withdrawal of ZH increased, there was a linear increase (P < 0.001) in final BW and carcass-adjusted final BW, but a linear decrease (P < 0.001) in ADG over the finishing period and over the ZH plus withdrawal period. Overall, HCW was 380 and 369 kg (P < 0.001) for ZH and control steers, respectively. However, the difference between ZH and control was 14, 17, 5, and 6 kg with 3, 10, 17, and 24 d withdrawal, respectively (ZH x withdrawal day, P = 0.09). Feeding ZH increased dressing percentage (65.8 vs. 64.6%; P < 0.001) and LM area (94.8 vs. 89.7 cm(2); P < 0.001), and decreased calculated yield grade (2.69 vs. 2.91; P = 0.03) and percentage of cattle grading USDA Choice (31.1 vs. 42.3%; P = 0.03) compared with controls. Small intestinal mass (g/kg of empty BW) was greater (P = 0.03) for steers fed ZH compared with controls. There were no other differences (P > or = 0.11) in mass of body components, expressed in kilograms or as a fraction of empty BW. In this experiment, improvements in animal performance and HCW due to feeding ZH were generally maintained when withdrawal was extended through 10 d.

Effects of zilpaterol hydrochloride and zilpaterol hydrochloride withdrawal time on beef carcass cutability, composition, and tenderness.

The impact of zilpaterol hydrochloride (ZH) on carcass yield, composition, and tenderness was evaluated using 384 beef steers in a randomized complete block design. Main effects were the addition of 0 or 8.3 mg/kg of ZH for the final 20 d of feeding and each inclusion level was paired with withdrawal periods of 3, 10, 17, or 24 d. The 2 animals with BW closest to the pen average were selected for carcass fabrication to determine carcass yield, composition, and tenderness. The carcasses from animals fed ZH had greater (P = 0.008) individual side weights. Carcass fat determinations were unchanged (P = 0.70) by ZH. Weights of the strip loin (P = 0.01), peeled tenderloin (P = 0.02), and top sirloin butt (P < 0.001) were all improved with ZH. When expressed as a proportion of carcass weight, ZH increased percentage of carcass in the top sirloin butt (P = 0.006), bottom sirloin tri-tip (P = 0.02), top inside round (P = 0.002), bottom round flat (P = 0.001), and flank steak (P = 0.02). A longer withdrawal time (WT) increased (P < 0.001) carcass weights. Shoulder clod weights were greatest (P < 0.001) with 17-d WT from ZH, whereas chuck roll weights were greatest (P = 0.02) at 17 and 24 d of WT. Peeled tenderloins, top sirloin butts, and eye of rounds responded to WT, with increased (P < 0.001) weights seen at 10 d of WT as compared with all other WT. Shear force values were greater at each of the 3 aging times, 7 d (P < 0.001), 14 d (P < 0.001), and 21 d (P = 0.003), in steaks from ZH-fed steers compared with control steers. Protein percentages were greater in ZH steaks (P = 0.03) and ZH ground beef trim (P < 0.001). Percent moisture was increased (P < 0.001) in strip loin steaks at 3 and 10 d WT. Ground beef trim had an increase (P = 0.04) in percent moisture and a decrease (P = 0.01) in percent fat at 10 d WT. Carcass weights and yields were improved with ZH feeding and may continue to improve even up to 10 d after withdrawal of the supplement. Tenderness was slightly reduced with ZH supplementation but was unaffected by WT. Zilpaterol hydrochloride can be a valuable supplement to finishing beef steers to improve carcass lean yields and composition.