ABSTRACT
OBJECTIVE: To evaluate the effectiveness of a step-by-step protocol for GT-guided transthoracic biopsy in verification of peripheral lung tumors. MATERIAL AND METHODS: A retrospective analysis of the results of GT-guided transthoracic biopsies of focal lung neoplasms was performed between October 2019 and December 2020. The analysis included the results of 176 biopsies in 158 patients. RESULTS: Primary biopsy was informative in 139 (87.97%) out of 158 patients. There were 155 (88.07%) informative and 21 (11.93%) non-informative biopsies. Lung adenocarcinoma was diagnosed in 41 (25.95%) patients, squamous cell carcinoma in 35 (22.15%) patients, and small cell carcinoma in 9 (5.7%) patients. There were 17 (10.76%) patients with uninformative biopsy results. Sensitivity, specificity and accuracy were 86%, 95.5%, and 87.8%, respectively. PPV was 98.9%, NPV - 58.3%. Various complications occurred after 65 (36.93%) out of 176 biopsies (95% CI 30.15-44.27). Pneumothorax followed by pleural drainage was detected after 8 (4.55%) biopsies. CONCLUSION: Accuracy of a step-by-step protocol for transthoracic biopsy was 88% that is not inferior to similar results in large-scale studies devoted to specialized navigation systems.
Subject(s)
Lung Neoplasms , Pneumothorax , Biopsy, Needle/adverse effects , Biopsy, Needle/methods , Humans , Image-Guided Biopsy/adverse effects , Lung/diagnostic imaging , Lung/pathology , Lung Neoplasms/pathology , Pneumothorax/etiology , Retrospective Studies , Sensitivity and Specificity , Treatment OutcomeABSTRACT
The aim of this study was to investigate and analyze the results of transthoracic needle biopsy of lung tumors under CT navigation. There were carried out more than 100 transthoracic needle biopsies of lung tumors. The analysis of immediate results of the applicability of this technique was performed. The average period of hospitalization after the puncture was 1.4 days (1-7). A number of pneumothorax that required drain- ing the pleural cavity was 8. The median of duration of drain- ing the pleural cavity was 6 of 8 patients (5-6.5) days. More severe complications and deaths were not. The histological conclusion was obtained in 100% of cases, in 72 patients the diagnosis of a malignant lung tumor was firstly verified, 12 cases showed a false-negative result. Diagnosis of lung cancer was excluded in 16 patients. The sensitivity of the method was 86%, specificity - 100% and accuracy - 88%. Therefore transthoracic needle biopsy of lung tumors with minimal risk to the patient allows receiving the morphological verification of peripheral lung tumors.
