Growth and modelling of spherical crystalline morphologies of molecular materials.

Crystalline, yet smooth, sphere-like morphologies of small molecular compounds are desirable in a wide range of applications but are very challenging to obtain using common growth techniques, where either amorphous films or faceted crystallites are the norm. Here we show solvent-free, guard flow-assisted organic vapour jet printing of non-faceted, crystalline microspheroids of archetypal small molecular materials used in organic electronic applications. We demonstrate how process parameters control the size distribution of the spheroids and propose an analytical model and a phase diagram predicting the surface morphology evolution of different molecules based on processing conditions, coupled with the thermophysical and mechanical properties of the molecules. This experimental approach opens a path for exciting applications of small molecular organic compounds in optical coatings, textured surfaces with controlled wettability, pharmaceutical and food substance printing and others, where thick organic films and particles with high surface area are needed.

[The effects of cryopreservation and embryo transplantation on the arterial pressure value in HSIAH strain rats with hereditarily induced arterial hypertension]. / Effekty kriokonservatsii i peresadki émbrionov na velichinu arterial'nogo davleniia u krys linii NISAG s nasledstvenno obuslovlennoi arterial'noi gipertenziei.

Homogeneous transplantation of embryos tissue exerted no effect on arterial pressure in adult Wistar rats and slightly increased the pressure in ISIAH male rats. Transplantation of male embryos of the ISIAH strain to Wistar rats significantly increased the blood pressure in the male ISIAH rats. Female ISIAH rats seem to possess a mechanism restricting the upper limit of the blood pressure. Cryopreservation of the ISIAH embryos seems to be a potent procedure for decreasing the blood pressure in this strain of hypertensive rats.

[Brain metabolism of sarcoma 45-bearing rats undergoing radiation and the effect of hyperthermia on the tumor]. / Nekotorye storony metabolizma mozga krys-opukholenositelei sarkomy 45 pri radiatsionnom i gipertermicheskom vozdeistviiakh na opukhol'.

Activity of hexokinase and acetylcholinesterase and pyridoxal co-enzyme content of brain subcellular fractions were studied in rats, bearing sarcoma 45, after local exposure of the tumor to 20 Gy X-radiation and microwave hyperthermia. The carbohydrate metabolism was sharply inhibited while the pyridoxal coenzyme content and acetylcholinesterase activity increased.

[Neurologic pathology in butterfly deformities of the body of the mid-thoracic vertebra (clinico-x-ray-anatomic observation)]. / O nevrologicheskoi patologii pri babochkovidnoi deformatsii tela srednegrudnogo pozvonka (kliniko-rentgenoanatomicheskoe nabliudenie).

Results of the clinico-roentgenological observation of butterfly-like deformity of the middle dorsal vertebra body (a rare congenital anomaly) are presented. In the presence of an infection the patient developed a spinal pathology (lower central paraparesis, parahypesthesia, disturbances of the functions of pelvic organs). The neurological symptoms were found to be due to an adhesive process in the spinal meninges at the level of the deformed vertebra and the secondary compression-ischemic myelopathy. The treatment consisted in injecting prednisolone under the spinal meninges. The patient's roentgenograms were compared with a macerated museum preparation of dorsal vertebrae.