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Article in Chinese | WPRIM (Western Pacific) | ID: wpr-682758

ABSTRACT

【Objective】To observe the effect of therapy of artificial menstrual cycle induction by Chinese medicine combined with assisted reproductive techniques(ART)on embryo implantation rate in in-vitro fertilization.【Methods】Sixtynine infertility patients were randomized into groups A(n=30)and B(n=39).Group B was treated with simple ART and group A received ART treatment after artificial menstrual cycle induction by Chinese medicine for 2~3 treatment courses.The therapy of artificial menstrual cycle induced by Chinese medicine respectivdy was carried out by applying Chinese medicine respectively with the actions of tonifying kidney,activating blood and removing stasis,tonifying kidney,and activating blood and regulating menstruation according to the ovarian cyclic changes of maturation of follicle,ovulation,formation of corpus luteum and atrophy of corpus luteum.After treatment,the medication time and dosage of gonadotropin,the number of retrieved oocytes,fertilization rate,cleavage rate,the number of fine quality embryo,embryo implantation rate and pregnancy rate were compared between the two groups.【Results】In group A,the embryo implantation rate was 27.0%,higher than 15.0% in group B(P0.05).【Conclusion】Therapy of artificial menstrual cycle induction by Chinese medicine combined with ART is helpful for the improvement and coordination of organic function,and thus increase embryo implantation rate in infertility patients.

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