Characteristic of the prevalence of J wave in apparently healthy Chinese adults.

BACKGROUND: The J wave has been seen in idiopathic ventricular fibrillation, Brugada syndrome, and early repolarization syndrome. Although these conditions share some ECG features, the clinical consequences are markedly different. J wave presentation in healthy subjects is not a rare phenomenon, although its characteristics are poorly understood. The aim of this study was to investigate the prevalence and the characteristics of the J wave in apparently healthy Chinese adults. METHODS: The study was comprised of 1817 consecutive healthy Chinese subjects undergoing annual routine medical examination from April 2006 to July 2006, including 1131 men and 686 women. Routine medical examination including ECG was performed. J wave was defined as a wave on the ECG that followed the QRS complex with amplitude of at least 0.05 mV for 0.03 sec. RESULTS: The prevalence of the J wave in all subjects was 7.26%. The prevalence of the J wave in males was significantly higher than in females (10.52 vs. 1.89%, p<0.01). The incidence of the J wave in the inferior leads (II, III, avF), right precordial leads (V1-V3), and left precordial leads (V4-V6) was 4.57, 0.50, and 2.20%, respectively. The J wave prevalence in the inferior leads was significantly higher than in the left and right precordial leads (both p<0.05). Moreover, the prevalence of the J wave had a positive correlation with age in all subjects (r=0.78, p<0.01). CONCLUSIONS: J wave presentation on the ECG of apparently healthy people is not a rare phenomenon and is more likely to be found in the elderly, in males, and more frequently occurs in the inferior leads than in left and right precordial leads.

The prevalence of J wave in apparently healthy subjects in Hubei province of China / 中华心血管病杂志

<p><b>OBJECTIVE</b>To observe the prevalence of J wave in apparently healthy subjects in Wuhan.</p><p><b>METHODS</b>The study subjects comprised of 1817 apparently healthy subjects (1131 males, mean age 46.38 +/- 15.81 years; 686 females, mean age was 42.77 +/- 14.15 years). ECG and routine medical examinations were performed. J wave was defined as a wave followed QRS complexes with amplitude of at least 0.05 mV and 0.03 s.</p><p><b>RESULTS</b>The overall incidence of J wave was 7.26%. The incidence of J wave in males was significantly higher than in females (10.53% vs. 1.87%, P < 0.01). The incidence of J wave in leads of inferior wall (II, III, avF), right wall (V(1 - 3)) and left wall (V(4 - 6)) was 4.57%, 0.50%, and 2.20%, respectively. J wave located in leads of inferior wall was more than in left and right walls (both P < 0.05). The incidence of J wave positively correlated with age (y = 0.1387x + 1.6318, r = 0.78, P < 0.01).</p><p><b>CONCLUSIONS</b>J wave is more likely seen in males and aged people and is more likely located in leads of inferior wall, than in leads of left and right walls.</p>

Effect of carvedilol on distribution and expression of connexin43 / 中华急诊医学杂志

Objective To observe the effect of carvedilol on the expression of Cx43 in rabbits with myocardial infarction and its association with ventricular arrhythmia.Method Thirty-six rabbits were randomly divided into three groups in equal number(n=12),namely,myocardial infarction(MI)group,carvedilol group and sham MI group.Rabbits of carvedilol group were administered with carvedilol 5 mg kg~(-1)?d~(-1)after MI induced,while no carvedilol was administered to the MI group.The following observations were made:(1)Cx43 density of the epicardial border zone measured by quantitative immnuoconfocal laser scanning,and(2)cx43 protein expression analyzed by western blot.Results(1)Under immunoconfocal laser microscope,the relative density of Cx43 was(0.16?0.06)% in the infarction group and was(0.32?0.11)% in the sham MI group [(0.68?0.15)%,both P