ABSTRACT
The growing occurrence of thrombophilic conditions in recent years, the discovery of new forms of thrombophilia, the involvement of intravascular microcoagulation in the development of many diseases make their study of primary importance especially in patients with chronic obstructive pulmonary disease and atherothrombosis. Such investigations would facilitate a deeper understanding of the detailed mechanisms of thrombosis in these patients and thereby contribute to the optimization of their treatment and prevention.
Subject(s)
Blood Coagulation Disorders/blood , Pulmonary Disease, Chronic Obstructive/blood , Thrombophilia/blood , Thrombosis/blood , HumansABSTRACT
The review of the data available in the literature dedicated to the problems of the diagnosis, clinical picture, and treatment of bronchial asthma (BA) in females during pregnancy. BA is shown to belong to the diseases whose pattern changes during pregnancy and despite that there are a great deal of papers on the above problem, the genesis of these changes has not been determined. Asthmatic attacks during gestation exert a significant negative impact on the development of pregnancy and the fetus; its main cause is hypoxia; however, there is no unambiguous evidence for this; today there are available several hypotheses that are presented in this paper. The data available in the literature show that most investigators consider it necessary to perform medical treatment for these disease; however, its nature has not been defined yet.
Subject(s)
Asthma , Pregnancy Complications , Asthma/complications , Asthma/diagnosis , Asthma/drug therapy , Female , Humans , Pregnancy , Pregnancy Complications/diagnosis , Pregnancy Complications/drug therapyABSTRACT
Validity of criteria of so called "pulmogenic hypertension" in chronic obstructive pulmonary diseases was assessed with the use of a questionnaire and simultaneous 24 hour monitoring of blood pressure and peak expiratory rate in 80 and 28 patients, respectively. This method of bifunctional monitoring allowed to study relationship between blood pressure level and degree of bronchial obstruction. The results did not confirm the presence of "pulmogenic hypertension" as a special form of arterial hypertension.
Subject(s)
Hypertension, Pulmonary/diagnosis , Hypertension, Pulmonary/physiopathology , Terminology as Topic , Adult , Aged , Diagnosis, Differential , Female , Humans , Hypertension, Pulmonary/etiology , Male , Middle Aged , Pulmonary Disease, Chronic Obstructive/complications , Severity of Illness IndexABSTRACT
Treatment of arterial hypertension in patients with concurrent chronic obstructive diseases of the lungs has limits in prescription of antihypertensive drugs. STAMLO--long-acting calcium antagonist--is proposed for monotherapy of mild and moderate hypertension in patients with bronchial asthma. The drug decreases hypertension in the greater and lesser circulation, improves bronchial permeability.
