Biochemical and Pharmacological Applications of Essential Oils in Human Health Especially in Cancer Prevention.

BACKGROUND: Essential oils (EOs) are aromatic, volatile and concentrated hydrophobic liquids extracted from plant material. EOs are also called as ethereal oils, volatile oils or aetherolea. EOs also play a crucial role in plant defence and signalling processes. They are mostly used in perfumes, cosmetics, soaps and other products for flavouring food, drinks, adding scents to incense and household cleaning products. EOs have a long medicinal history. METHODS: Reported research literature and online contents related to the use of EOs for their biochemical pharmacological applications in cancer prevention therapy were reviewed. The most relevant and updated citations were included in this review. RESULTS: This review elaborates the various types of EOs, their biochemical characteristics, and pharmacology. Medicinal benefits of essential oil products range from various skin treatments to different types of therapies for cancer and are dependent entirely on historical backgrounds of use of EOs for these properties. EOs have antimicrobial, anticancer, antioxidant, antiparasitical, insecticidal, anti-inflammatory, viricidal, fungicidal, wound healing, antihypertensive, analgesic properties and other medicinal properties. The efficiency of EOs in medical treatments and treatment of cancers are these days a subject of interest in most countries. CONCLUSION: This review elaborated the potentials of EOs in regulating cancer cell growth and have explored the probable EOs that can be used in drug development.

One Versus Two Photon Control of Dynamical Tunneling: Influence of the Irregular Floquet States.

A useful approach to control quantum processes involves driving systems with two colored laser fields and varying the relative phase between the fields to control the quantum interferences. A particularly interesting class of bichromatic control schemes involves the so-called M versus N-photon control that results in laser-induced symmetry breaking and leads to directed transport; however, recent studies have shown that the mechanism of laser-induced symmetry breaking has a common classical and quantum origin. In this context, a relevant question is the extent to which such a detailed classical-quantum correspondence holds if the process to be controlled involves quantum tunneling. In this work, we address this issue in terms of controlling dynamical tunneling between field-induced islands of stability in the classical phase space of a model system, a periodically driven pendulum. This is also a paradigmatic model for Hamiltonian ratchets wherein the islands of stability, that is, nonlinear resonances, play a crucial role in the observed directed transport. We compute an appropriate control landscape for the process and show that despite breaking the relevant symmetries, there exist regions in the control landscape where the control fails. The lack of control can be understood in terms of the phase-space nature of the quantum Floquet states that participate in the dynamics of the initial wavepacket. We argue that robust regions of no control arise due to the phenomenon of chaos-assisted tunneling and comment on the possible influence of such regions on the directed transport in the model system.

Andrographolide and analogues in cancer prevention.

Andrographis paniculata is a medicinal plant traditionally used for treatment of cough and cold, fever, laryngitis, and several infectious diseases. Extracts of A. paniculata have shown versatile potency against various diseases including cancer. The active biomolecules of A. paniculata mainly are lactone and diterpene. Andrographolide and analogues have been widely used for prevention of different diseases. Andrographolides have shown potent antiinflammatory and anticancer activities. It showed potentials as chemopreventive agents by suppressing growth of cancer cells by inhibiting NF-kappaB, PI3K/AKT and other kinase pathways and by inducing apoptosis. Andrographolide induced both intrinsic and extrinsic apoptosis pathway in different cancer cells via expression of different anti-apoptotic protein like Bax, p53, and activated caspases. Andrographolide was successfully used as an antineoplastic drug in cancer chemotherapy. Andrographolide inhibited the growth of human breast, prostate, and hepatoma tumors. Andrographolide and analogues need to be subjected to further clinical and biomedical studies in cancer chemoprevention. Andrographolide could be potent anticancer agent when used in combination with other chemotherapeutic agents.

Use of assistive technologies in academic libraries: a survey.

The present article attempts to highlight the use of assistive technologies in academic libraries in India, the United Kingdom, the United States, and Canada. It dwells upon the use and importance of assistive technologies in general and their use for visually challenged learners in particular. Further, it gives suggestions for implementing assistive technologies in academic libraries for making visually challenged students self-reliant learners in accomplishing their academic and research pursuits. The present study adopted convenience sampling for collecting the data, which was collected between December 15, 2012 and January 18, 2013.