Low-cost compressive sensing imaging based on spectrum-encoded time-stretch structure.

A low-cost compressive sensing imaging (CSI) system based on spectrum-encoded time-stretch (SETS) structure involving cascaded Mach-Zehnder Interferometers (MZIs) for spectral domain random mixing (also known as the optical random pattern generator) is proposed and experimentally demonstrated. A proof-of-principle simulation and experiment is performed. A mode-locked laser with a repetition rate of 50MHz and low-cost cascaded MZIs as the key devices enable fast CSI system. Data compression ratio from 6% to 25% are obtained using proposed CSI based SETS system. The proposed design solves the big data issue in the traditional time-stretch system. It has great potential in fast dynamic phenomena with low-cost and easy-access components.

Self-Correcting Recurrent Neural Network for Acute Kidney Injury Prediction in Critical Care.

Background. In critical care, intensivists are required to continuously monitor high-dimensional vital signs and lab measurements to detect and diagnose acute patient conditions, which has always been a challenging task. Recently, deep learning models such as recurrent neural networks (RNNs) have demonstrated their strong potential on predicting such events. However, in real deployment, the patient data are continuously coming and there is no effective adaptation mechanism for RNN to incorporate those new data and become more accurate.Methods. In this study, we propose a novel self-correcting mechanism for RNN to fill in this gap. Our mechanism feeds prediction errors from the predictions of previous timestamps into the prediction of the current timestamp, so that the model can "learn" from previous predictions. We also proposed a regularization method that takes into account not only the model's prediction errors on the labels but also its estimation errors on the input data.Results. We compared the performance of our proposed method with the conventional deep learning models on two real-world clinical datasets for the task of acute kidney injury (AKI) prediction and demonstrated that the proposed model achieved an area under ROC curve at 0.893 on the MIMIC-III dataset and 0.871 on the Philips eICU dataset.Conclusions. The proposed self-correcting RNNs demonstrated effectiveness in AKI prediction and have the potential to be applied to clinical applications.

All-fiber online Raman sensor with enhancement via a Fabry-Perot cavity.

In this Letter, a novel all-fiber online Raman sensor with significant signal enhancement via a Fabry-Perot (FP) cavity is proposed and demonstrated. The FP cavity structure is formed by inserting a long-pass coated fiber and a gold-plated capillary into a silver-lined capillary with a gap. A corroded single-mode fiber is inserted into the gold-plated capillary to guide the excitation light into the FP cavity. The multiple reflections of excitation light in the FP cavity have significantly increased the interaction volume between the light and the sample. Experiment results have demonstrated an enhancement factor of 5 times in the detected Raman signal for ethanol compared to that measured using the silver-lined hollow-core fiber-based Raman cell without FP cavity, or 86 times compared with direct detection using a bare fiber tip. The measurement results are in good agreement with theoretical analyses. This Raman sensor with signal enhancement via the FP cavity has the potential to realize rapid sample replacement and online detection with high sensitivity and high accuracy for biochemical applications.

Highly efficient free-space fiber coupler with 45° tilted fiber grating to access remotely placed optical fiber sensors.

In this work, a 45° tilted fiber grating (TFG) is used as a waveguide coupler for the development of a portable interrogation system to access remotely placed optical fiber sensors. The TFG is directly connected to a remote fiber sensor and serves as a highly efficient light coupler between the portable interrogation unit and the sensor. Variation of strain and temperatures are measured with a standard fiber Bragg grating (FBG) sensor, which serves as a remotely placed optical sensor. A light beam from the interrogation unit is coupled into the TFG by a system of lenses, mirrors and optical collimator and acted as the input of the FBG. Reflected light from the FBG sensor is coupled back to the interrogation unit via the same TFG. The TFG is being used as a receiver and transmitter of light and constituent the key part of the system to connect "light source to the optical sensor" and "optical sensor to detector." A successful demonstration of the developed system for strain and temperature sensing applications have been presented and discussed. Signal to noise ratio of the reflected light from the sensors was greater than ∼ 40 dB.

Single-axis soliton molecule and multiple solitons generation from a vector fiber laser.

We investigate various patterns of vector solitons arising in a passively mode-locked fiber laser based on semiconductor saturable absorber mirror (SESAM). By properly adjusting the cavity parameters including the pump power and intra-cavity birefringence, the fundamental vector solitons, vector soliton molecules, and macroscopic vector solitons can be separately observed. In particular, both vector soliton molecule and macroscopic vector solitons exhibit multi-pulse structure along one polarization axis while there occurs single pulse profile at its orthogonal polarization component. Thus, they can be treated as "1 + 2" and "1+n" vector solitons. Moreover, the size of the macroscopic solitons can be manipulated from half of the cavity to even the whole cavity. The generation mechanisms of these vector soliton patterns are also investigated.

Simultaneous achievement of an ultrashort length and a high extinction ratio polarization splitter based on the dual-core photonic crystal fiber with Ge20Sb15Se65 glass.

A polarization splitter based on dual-core photonic crystal fiber with ${{\rm Ge}_{20}}{{\rm Sb}_{15}}{{\rm Se}_{65}}$ glass is proposed to realize ultrashort length and high extinction ratio simultaneously at the common wavelength of 1.55 µm. The characteristics of the polarization splitter have been investigated by the finite element method. By tailoring the structure parameters on the performance of the splitter, the optimized parameters are obtained to analyze the birefringence, the coupling length, the normalized power transfer, and the extinction ratio. A comparison with other designs demonstrates the advantages of our polarization splitter, which can find potential applications in optical communication systems, optical fiber sensing, etc.

Semiconductor-laser-based hybrid chaos source and its application in secure key distribution.

An analog-digital hybrid optical chaos source and a corresponding secure key distribution (SKD) scheme are proposed. An analog-digital hybrid electro-optic feedback loop is introduced to enhance the robustness of the chaotic semiconductor lasers. The source, which can adopt robust digital synchronization strategies, could generate a broadband analog optical chaotic signal of high dynamical complexity. Furthermore, the source reduces the requirement on the processing speed of digital components and simplifies the hybrid system structure markedly. For demonstrating, we build a SKD system with the proposed chaos source. Since this SKD scheme is compatible with digital optical networks, the commercially available communication techniques can help to make it insensitive to impairments in fiber optic links. This feature has potential in long-haul SKD.

Highly sensitive gas refractometers based on optical microfiber modal interferometers operating at dispersion turning point.

In most fiber-optic gas sensing applications where the interested refractive index (RI) is ~1.0, the sensitivities are greatly constrained by the large mismatch between the effective RI of the guided mode and the RI of the surrounding gaseous medium. This fundamental challenge necessitates the development of a promising fiber-optic sensing mechanism with the outstanding RI sensitivity to achieve reliable remote gas sensors. In this work, we report a highly sensitive gas refractometer based on a tapered optical microfiber modal interferometer working at the dispersion turning point (DTP). First, we theoretically analyze the essential conditions to achieve the DTP, the spectral characteristics, and the sensing performance at the DTP. Results show that nonadiabatic tapered optical microfibers with diameters of 1.8-2.4 µm possess the DTPs in the near-infrared range and the RI sensitivities can be improved significantly around the DTPs. Second, we experimentally verify the ultrahigh RI sensitivity around the DTP using a nonadiabatic tapered optical microfiber with a waist diameter of ~2 µm. The experimental observations match well with the simulation results and our proposed gas refractometer provides an exceptional sensitivity as high as -69984.3 ± 2363.3 nm/RIU.

Simultaneous achievement of highly birefringent and nonlinear photonic crystal fibers with an elliptical tellurite core.

A novel photonic crystal fiber (PCF) with an elliptical tellurite core is proposed to realize high birefringence and high nonlinearity simultaneously as well as low confinement loss at the wavelength of 1.55 µm. The guiding properties, such as the birefringence, the nonlinearity, and the confinement loss, have been investigated by using the full vectorial finite element method. The results show that the birefringence and the nonlinear coefficient can be up to 7.57×10-2 and 188.39 W-1 Km-1, respectively, and the confinement loss can be only 10-9 dB/m. The proposed PCF can find potential applications in optical fiber sensing, polarization-maintaining transmission, and super-continuum generation.

High-sensitivity birefringent and single-layer coating photonic crystal fiber biosensor based on surface plasmon resonance.

A birefringent single-layer coating photonic crystal fiber biosensor based on surface plasmon resonance is proposed to realize high sensitivity, which is easy to implement, in that only gold is deposited externally. The birefringent nature of the structure provides the sensor with high sensitivity. The results show that the biosensor can obtain the wavelength sensitivity of 15180 nm/refractive index unit (RIU) and high linearity with the analyte RI range of 1.40-1.43, corresponding to the resolution of 5.6818×10-6 RIU. Owing to the high sensitivity and simple structure, the proposed sensor can find important applications in biochemical and biological analyte detection.

Multifiber angular compounding optical coherence tomography for speckle reduction.

We report on an integrated fiber optic design to implement multifiber angular compounding optical coherence tomography, which enables angular compounding for speckle reduction. A multi-facet fiber array delivers three light beams to the sample with different incident angles. Back-reflective/back-scattered signals from these channels were simultaneously detected by a three-channel spectrometer. The axial and lateral resolution was measured to be ∼3 and ∼3.5 µm, respectively, in air with ∼100 dB sensitivity. We conducted ex vivo experiments on a rat esophagus to demonstrate a contrast to noise improvement of 1.58.

Spatial-division multiplexed Brillouin distributed sensing based on a heterogeneous multicore fiber.

We have experimentally investigated spatial-division multiplexed (SDM) Brillouin optical time-domain analysis in a heterogeneous multicore fiber whose central core and six outer cores are made from different preforms, showing a ∼70 MHz Brillouin frequency shift (BFS) difference between them. It reveals that the heterogeneous central core and the outer cores have different temperature sensitivities, but their strain sensitivities are almost the same. By making use of the distinct temperature coefficients of these two kinds of cores, simultaneous and discriminative temperature and strain measurements are achieved. The bending-induced Brillouin gain spectrum (BGS) broadening issue in off-center cores has been clarified, and a solution has been proposed to eliminate the uncertainty caused by a bending-induced BFS shift, by averaging the BFS variations of two symmetrical outer cores. We show a new perspective for discriminative measurement in Brillouin distributed sensors based on SDM solutions.

Electro-optic chaotic system based on the reverse-time chaos theory and a nonlinear hybrid feedback loop.

A novel electro-optic chaos source is proposed on the basis of the reverse-time chaos theory and an analog-digital hybrid feedback loop. The analog output of the system can be determined by the numeric states of shift registers, which makes the system robust and easy to control. The dynamical properties as well as the complexity dependence on the feedback parameters are investigated in detail. The correlation characteristics of the system are also studied. Two improving strategies which were established in digital field and analog field are proposed to conceal the time-delay signature. The proposed scheme has the potential to be used in radar and optical secure communication systems.

Switchable thulium-doped fiber laser from polarization rotation vector to scalar soliton.

We experimentally demonstrate switchable temporal soliton generation from a thulium-doped fiber laser (TDFL), using carbon nanotubes as the mode-locker. With the help of residual polarization dependent loss of a wavelength division multiplexer, a weak nonlinear polarization rotation (NPR) effect can be achieved within the laser cavity, which may provide joint contribution for passive mode-locking operation. By finely adjusting the polarization to alter the strength of NPR-based saturable absorption, the TDFL either approaches the operation regime of scalar soliton with strong NPR effect, or generates polarization rotation locked vector soliton (PRLVS) with weak NPR effect. The scalar solitons and PRLVSs possess 3-dB optical spectrum bandwidth of 2.2 nm and 2 nm, pulse-width of 1.8 ps and 2 ps, respectively. Moreover, the PRLVSs demonstrate a typical energy exchange between two polarized components on optical spectra and a period-doubling feature in time domain. Such operation principle can also be used in 1550 nm band fiber lasers and other nonlinear systems.

High-frequency reverse-time chaos generation using an optical matched filter.

The optical reverse-time chaos is realized by modulating a binary pseudo-random bit sequence onto an optical carrier, and then driving an optical matched filter. The filter is demonstrated experimentally by using two fiber Bragg gratings and a Fourier-domain programmable optical processor. The complexity relationship between the binary input sequence and the output chaos signal is studied. This approach could be a novel way to generate a high speed repeatable and controllable optical chaos signal, which has the potential to be used in optical secure communication systems.

Dual spectrometer system with spectral compounding for 1-µm optical coherence tomography in vivo.

1 µm axial resolution spectral domain optical coherence tomography (OCT) is demonstrated for in vivo cellular resolution imaging. Output of two superluminescent diode sources is combined to provide near infrared illumination from 755 to 1105 nm. The spectral interference is detected using two spectrometers based on a Si camera and an InGaAs camera, respectively. Spectra from the two spectrometers are combined to achieve an axial resolution of 1.27 µm in air. Imaging was conducted on zebra fish larvae to visualize cellular details.

Colorimetric surface plasmon resonance imaging (SPRI) biosensor array based on polarization orientation.

A colorimetric surface plasmon resonance (SPR) imaging biosensor array based on polarization orientation rotation is presented in this paper. It measures the spectral characteristic variations caused by the steep phase difference between the p- and s-polarization occurring at surface plasmon excitation. It provides one-order of magnitude sensor resolution improvement comparing to existing phase-sensitive SPR imaging sensors and the two-dimensional (2D) sensing capability of the imaging sensor enables multiplex, high throughput array based simultaneous detection for a range of different bio-molecular interactions. Experiments on the binding interactions detection between anti-bovine serum albumin (anti-BSA) and BSA antigen have been performed. All binding interactions occurred at 5×4 protein array were real-time monitored simultaneously. A sensor resolution of 8.26ng/ml (125pM) has been demonstrated, which is one-order of magnitude (12 times) better than the detection limit reported by existing phase-sensitive SPR imaging sensors in the literature, while no time-consuming phase modulation and phase extraction processes are required. Furthermore, the optical colorimetric image read-out of the sensor is easy to be identified by the end users comparing to conventional intensity or phase information. The colorimetric SPR imaging biosensor array can find promising potential applications in high throughput clinical disease diagnosis, protein biomarkers screening and drug screening.

Bandwidth analysis of waveguide grating coupler.

The bandwidth of planar waveguide grating couplers is theoretically investigated based on the rigorous grating theory. We observe that the bandwidth behavior is not only determined by the grating coupler intrinsic properties, but also affected by the fiber parameters such as position, beam waist and Numerical Aperture. The rigorous bandwidth formula is derived. By analyzing the formula, several practical guidelines are proposed for grating coupler design and fiber operation in order to achieve wideband performance.

Radially graded index whispering gallery mode resonator for penetration enhancement.

This paper theoretically analyzes a hollow cylindrical whispering gallery mode resonator with radially inhomogeneous cladding. We propose an index profile of n(r) = b/r to enhance field penetration towards the resonator core. With such index profile, externally coupled evanescent wave can easily penetrate the resonator cladding without any potential barrier.

Plasmonic optical trap having very large active volume realized with nano-ring structure.

The feasibility of using gold nano-rings as plasmonic nano-optical tweezers is investigated. We found that at a resonant wavelength of λ=785 nm, the nano-ring produces a maximum trapping potential of ~32k(B)T on gold nanoparticles. The existence of multiple potential wells results in a very large active volume of ~10(6) nm(3) for trapping the target particles. The report nano-ring design provides an effective approach for manipulating nano-objects in very low concentration into the high-field region and is well suited for integration with microfluidics for lab-on-a-chip applications.