ABSTRACT
In a prospective double-blind study, 27 patients with alcoholic hepatitis were randomized for 6-methylprednisolone (12 patients) or placebo treatment (15 patients). The mortality was 50% among steroid treated patients and 47% in the control group (P less than .05). The role of liver biopsy feasibility at selection is emphasized since the mortality in this group was 10% as opposed to 71% when the procedure was contraindicated (P less than .01). Complications in the steroid-treated subjects were similar quantitatively and qualitatively to those observed in the control series.
Subject(s)
Hepatic Encephalopathy/drug therapy , Hepatitis, Alcoholic/drug therapy , Methylprednisolone/therapeutic use , Acute Disease , Adult , Biopsy , Clinical Trials as Topic , Double-Blind Method , Female , Hepatic Encephalopathy/etiology , Hepatitis, Alcoholic/complications , Hepatitis, Alcoholic/mortality , Humans , Male , Methylprednisolone/adverse effects , Middle Aged , Placebos , Prospective StudiesABSTRACT
The 161A strain of Naegleria isolated from a human nasal swab and reported earlier was further studied for its growth pattern, cyst-wall appearance, cytopathic effect on primary monkey kidney cells, and pathogenicity in mice. Results obtained in the study establish the pathogenic status of this strain. This constitutes the first isolation of a pathogenic Naegleria from a human nasal cavity.
Subject(s)
Amoeba/isolation & purification , Nose/parasitology , Amoeba/growth & development , Amoeba/pathogenicity , Amoeba/ultrastructure , Animals , Cells, Cultured , Culture Media , Haplorhini , Humans , MiceSubject(s)
Arthritis/etiology , Hepatitis A/complications , Urticaria/etiology , Adolescent , Adult , Ankle Joint , Biopsy , Female , Finger Joint , Hepatitis A/pathology , Humans , Knee Joint , Liver/pathology , Male , Middle Aged , Neurologic Manifestations , Pain , Skin Manifestations , Time FactorsABSTRACT
The intensities of the 7147 Å Ar i and 4806 Å Ar ii lines obtained from wall-stabilized arcs at pressures of 0.2 to 5 atm are presented in an Olsen-Richter diagram. Departures from equilibrium are evident at electron densities below 5 × 1016 cm-3. The assumption of equilibrium at higher electron densities leads to transition probabilities in fair agreement with lifetime measurements.
Subject(s)
Amebiasis/complications , Meningoencephalitis/etiology , Swimming , Adolescent , Adult , Humans , Male , Meningoencephalitis/microbiology , VirginiaSubject(s)
Disease Outbreaks/epidemiology , Trichinellosis/epidemiology , Alaska , Humans , Mississippi , Missouri , Retrospective Studies , WisconsinABSTRACT
In order to derive transition probabilities from intensity measurements of Ar I lines made by Dieke and Crosswhite, new transition probabilities for 26 lines from high levels in Ar I have been measured in a high current constricted arc. With these data, relative level populations of Ar I in Dieke and Crosswhite's rnicrewave discharge are determined and transition probabilities for 240 lines of Ar I in the wavelength range 4100 to 9800 Å are derived. The new values are compared with other published values.
