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2.
Akush Ginekol (Mosk) ; (11): 49-51, 1991 Nov.
Article in Russian | MEDLINE | ID: mdl-1814229

ABSTRACT

The author presents data on the transplacental passage of dimethylformamide (DMFA) and toluene in combined exposure at the level of the maximum allowable concentrations. A new method for measurements of chemicals in animal biomedia is suggested. The permeability index for DMFA has made up 37.1%, that for toluene 90.2%. The results recommend the new method for experimental and clinical measurements of chemicals.


Subject(s)
Dimethylformamide/pharmacokinetics , Placenta/metabolism , Toluene/pharmacokinetics , Administration, Inhalation , Animals , Chromatography, Gas , Dimethylformamide/analysis , Female , Fetus/chemistry , Fetus/metabolism , Placenta/chemistry , Pregnancy , Rats , Toluene/analysis
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