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J Am Acad Dermatol ; 22(2 Pt 2): 334-7, 1990 Feb.
Article in English | MEDLINE | ID: mdl-2303588

ABSTRACT

Extramedullary hematopoiesis was found in the cutaneous papulonodular eruption of a 72-year-old man with myelofibrosis. This is the first reported case to show a preponderance of atypical megakaryocytes in skin lesions. The patient was also unusual in that he had marked generalized lymphadenopathy. The skin lesions almost disappeared after treatment with hydroxyurea.


Subject(s)
Hematopoiesis, Extramedullary , Primary Myelofibrosis/physiopathology , Aged , Biopsy , Hematopoiesis, Extramedullary/drug effects , Humans , Hydroxyurea/therapeutic use , Male , Megakaryocytes/pathology , Skin/physiopathology
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