1.
Bull Exp Biol Med
; 155(2): 187-9, 2013 Jun.
Article
in English
| MEDLINE
| ID: mdl-24130985
ABSTRACT
Experimental post-traumatic arthritis was accompanied by overexpression of pro-inflammatory cytokines and imbalance in the collagen metabolism. Intraarticular injection of mexidol prevented free-radical degradation of collagen structures, contributed to activation of collagen synthesis and cartilage repair, and reduced the severity of inflammatory changes in the joint and the degree of secondary alteration of tissue structures.
Subject(s)
Arthritis, Experimental/drug therapy , Inflammation/drug therapy , Knee Joint/metabolism , Picolines/therapeutic use , Animals , Arthritis, Experimental/chemically induced , Cartilage/metabolism , Cartilage, Articular/metabolism , Collagen/metabolism , Female , Hydroxyproline/metabolism , Injections, Intra-Articular , Interleukin 1 Receptor Antagonist Protein/blood , Interleukin-1beta/blood , Interleukin-4/blood , Knee Joint/drug effects , Knee Joint/pathology , Male , Rats , Tumor Necrosis Factor-alpha/blood
2.
Med Parazitol (Mosk)
; (2): 49-52, 2008.
Article
in Russian
| MEDLINE
| ID: mdl-18561407
Subject(s)
Anticoagulants/poisoning , Blood Coagulation Disorders/veterinary , Rodent Diseases/chemically induced , Rodentia , Rodenticides/poisoning , Animals , Blood Coagulation Disorders/chemically induced , Blood Coagulation Disorders/pathology , Death , Female , Male , Mice , Rats , Rodent Diseases/pathology , Time Factors
3.
Gig Tr Prof Zabol
; 14(8): 61, 1970 Aug.
Article
in Russian
| MEDLINE
| ID: mdl-5508061
