Subject(s)
Diabetes Mellitus, Type 2/complications , Hemoglobins, Abnormal/genetics , Pheochromocytoma/complications , alpha-Thalassemia/complications , alpha-Thalassemia/genetics , Diabetes Mellitus, Type 2/diagnosis , Diabetes Mellitus, Type 2/drug therapy , Humans , Male , Middle Aged , Pheochromocytoma/diagnosis , Pheochromocytoma/surgery , Portugal , Treatment Outcome , alpha-Thalassemia/diagnosisABSTRACT
The paper deals with the experience with synthetic resolving Caproag suture threads which have antibacterial properties for suturing the uterine section during Caesarean and other gynecological operations. There is evidence for its high efficacy in optimal tissue regeneration. Caproag was used in the most life-threatening infectious and septic complications. With this, a reduction has been achieved in the incidence of postoperative pyo-inflammatory diseases, which makes Caproag compare favourably with the conventional suture threads catgut and vicryl.
Subject(s)
Sutures , Uterus/surgery , Catgut , Female , Gynecology/instrumentation , Humans , Materials Testing , Obstetrics/instrumentation , Polyglactin 910 , Postoperative Complications/prevention & controlABSTRACT
The paper gives data on the composition and strength characteristics and experimental and clinical findings of resolving antimicrobial suture materials, such as Capromed-type one, based on the modified caproic fiber coated by the biocompatible polymer PPB-1 which contains antimicrobial drugs. Capromed threads are demonstrated to have high strength characteristics and resolve in the body within 8-9 months. Coating the modified caproic fibers with the biocompatible copolymer imparts them pseudomonfilament characteristics and prevents the penetration of cellular elements to the thickness of threads. The content of antibacterial agents in the polymer coating confers prolonged antibacterial properties on Capromed. Desorption of antimicrobial agents from Capromed is conducive to more favourable healing, prevents the development of ligature fistulas, favours an over 4-fold reduction in the incidence of wound complications, as compared to the controls.