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Mikrobiol Z ; 74(6): 90-8, 2012.
Article in English | MEDLINE | ID: mdl-23293832

ABSTRACT

The immunomodulatory properties of Lactobacillus delbrueckii subsp. bulgaricus IMVB-7281, Lactobacillus casei IMV B-7280, Lactobacillus acidophilus IMV B-7279, Bifidobacterium animales VKL and B. animales VKB strains on the models of experimental staphylococcosis infection in mice were determined. It was found that after the mice, infected with staphylococcus, were treated by some probiotic strains of lacto- and bifidobacteria, a normalization of functional activity of phagoctic cells system and increase of the endogenous interferon production were observed. L. delbrueckii subsp. bulgaricus IMVB-7281, L. casei IMVB-7280, L. acidophilus IMV B-7279, B. animales VKB and B. animales VKL are promising for the development of probiotics, effective against staphylococci and for the immunity correction.


Subject(s)
Bifidobacterium/physiology , Lacticaseibacillus casei/physiology , Lactobacillus acidophilus/physiology , Macrophages, Peritoneal/drug effects , Probiotics/therapeutic use , Staphylococcal Infections/immunology , Administration, Oral , Animals , Antibiosis , Cell Count , Female , Immunomodulation/drug effects , Injections, Intraperitoneal , Interferons/biosynthesis , Interferons/immunology , Killer Cells, Natural/drug effects , Killer Cells, Natural/immunology , Macrophages, Peritoneal/immunology , Mice , Mice, Inbred BALB C , Peritoneum/drug effects , Peritoneum/immunology , Peritoneum/microbiology , Probiotics/administration & dosage , Spleen/drug effects , Spleen/immunology , Spleen/microbiology , Staphylococcal Infections/microbiology , Staphylococcal Infections/therapy , Staphylococcus/drug effects
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