ABSTRACT
The case of a clear cell carcinoma of a minor salivary gland, at the basis of the tongue, is described, which represents 1% of malignant tumours of salivary glands. The biological behaviour is not very aggressive and development, which is very slow, is usually asymptomatic, and, indeed, the tumour often reaches considerable dimensions before being diagnosed. There are rare cases of local recurrence and distant metastases. Cases of salivary glands which have become sites of secondary localization of a clear cell tumour, originating in the kidneys, have been described. The interest in the form described here stems from the slow evolution and the considerable dimensions reached by the tumour before being diagnosed, despite development in a breathing or digestive area such as the oralpharyngeal tract. In the present case, computed axial tomography and nuclear magnetic resonance were used to reach the diagnosis. The patient was submitted to surgical treatment. In the differential diagnosis, it is necessary, from a pathological point of view, to take into consideration other neoplastic formations, such as acinar cell adenocarcinoma, epithelial-myoepithelial carcinoma, clear cell oncocytoma, sebaceous adenoma and sebaceous carcinoma.
Subject(s)
Adenocarcinoma, Clear Cell/pathology , Neoplasm Invasiveness , Salivary Gland Neoplasms/pathology , Tongue Neoplasms/pathology , Adenocarcinoma, Clear Cell/surgery , Aged , Endoscopy/methods , Humans , Magnetic Resonance Imaging , Male , Neoplasm Invasiveness/pathology , Plastic Surgery Procedures/methods , Salivary Gland Neoplasms/surgery , Tongue Neoplasms/surgery , Video-Assisted Surgery/methodsABSTRACT
Two cases of sarcoidosis, presenting with parotid gland enlargement and keratoconjunctivitis sicca, are here described. The difficulty encountered in making correct diagnosis is then stressed. The diagnostic value of invasive and non invasive techniques in the study of parotid gland pathology and function in sarcoidosis is then reviewed.
Subject(s)
Keratoconjunctivitis Sicca/etiology , Keratoconjunctivitis/etiology , Parotid Diseases/etiology , Sarcoidosis/complications , Adult , Diagnosis, Differential , Female , Humans , Male , Middle Aged , Sarcoidosis/diagnosis , Sjogren's Syndrome/diagnosisABSTRACT
Two cases of achalasia of the lower third of the oesophagus are presented. Leucoplakia was encountered in one of the cases. The clinical, aetiopathogenic and x-ray diagnostic aspects of achalasia are described in relation to the possibility that it may be associated with neoplasia or pre-cancerous alterations. In both the above cases, early dysphagia was encountered.
