[The interaction of pathogenic microorganisms with the sorbent polymethylsiloxane]. / Izuchenie vzaimodeistviia patogennykh mikroorganizmov s sorbentom polimetilsiloksanom.

The method of electron microscopy has been used to study adhesion of the microbic cells of standard strains of Staphylococcus aureus, Escherichia coli and fungi of genus Candida on the organosilicon sorbent polymethylsiloxane (PMS) and medicamentous complex containing it. This complex contains furazolidone and metronidazole immobilized on silver ions-modified PMS. It is shown that the adhesion of microorganisms is accompanied by their destruction whose rate on pure PMS and medicamentous complex is different. Using experimental data the assumptions are advanced concerning the mechanism of the PMS interaction with Gram-positive and Gram-negative microorganisms as well as with fungi of genus Candida.

[The use of mathematical modelling and prediction for assessing the efficacy of the treatment of periodontitis]. / Primenenie matematicheskogo modelirovaniia i prognozirovaniia dlia otsenki éffektivnosti lecheniia periodontita.

The statistical prediction and mathematical modelling techniques were applied to the analysis of the results of treatment of periodontitis. The afflicted focus cross-sectional area (as measured by X-ray film) was taken as a variable. A total of 40 patients were divided into 2 groups. Computer analysis allowed developing a mathematical model of the afflicted focus ossification under different therapeutical approaches.

[The morphologic basis for the use of immobilized drug preparations in therapeutic oral medicine]. / Morfologicheskoe obosnovanie primeneniia immobilizovannykh lekarstvennykh preparatov v terapevticheskoi stomatologii.

The response of connective tissue on drugs with different action spectra (gentamycin, furazolidon, mefenamin sodium) immobilized on the poliurethane basis was studied experimentally. Immobilized forms of the drugs created favorable conditions for faster wound cicatrization.