ABSTRACT
The aim of the present work was to identify possible associations between individual balances in the activity of the positive and negative reinforcement motivation systems using a method based on emotional modulation of the startle reaction (EMSR) by motivationally significant emotionally positive and negative contextual visual stimuli and measures of cardiovascular system activity. Studies were performed using healthy males (mean age 30.29 +/- 9.8 years) with normal and first-episode excessive increases in arterial blood pressure (systolic blood pressure to greater than 140 mmHg, diastolic to greater than 90 mmHg). Cluster analysis of EMSR data identified groups of individuals with different activity profiles for the positive and negative reinforcement systems. Groups of subjects with changes in the balance of activity towards a lower level of positive reinforcement system activity (smaller startle reflexes to positive contextual stimuli) or a higher level of negative reinforcement system activity (larger startle reactions to threatening contextual stimuli) showed significantly greater baseline SBP and DBP. The possible mechanisms of the modulatory influences of the balance of system activities on autonomic vascular regulatory processes are discussed.
Subject(s)
Blood Pressure/physiology , Emotions/physiology , Motivation , Reflex, Startle/physiology , Adult , Electromyography , Galvanic Skin Response/physiology , Heart Rate/physiology , Hemodynamics/physiology , Humans , Male , Muscle Contraction/physiology , Oculomotor Muscles/physiology , Photic Stimulation , Reinforcement, Psychology , Smoking/physiopathology , Young AdultABSTRACT
Fail of fast recovering to normal state after aversive event is the key feature of individual intolerance to emotional stress. Within the framework of this idea, dynamics of the arterial blood pressure reactivity was studied studied using defensive reaction of the cardiac defense response elicited by strong aversive acoustic stimuli. Dynamical patterns of cardiovascular responses observed in this reaction makes made it possible to perform affective chronometry of defensive arousal. Healthy male volunteers with normal arterial blood pressure and patients with firstly diagnosed and untreated essential hypertension were studied. The beat-by-beat dynamics of blood pressure values were registered by means of finger-cuff Finapres technology. It was shown that among healthy individuals with normal resting blood pressure values hyperreactive persons with delayed late systolic and diastolic blood pressure increases ocurred. It was suggested that similiarity of delayed pressor effects ofhypereactive healthy individuals and those of hypertension patients incate a high risk of essential hypertension in highly reactive individuals.
Subject(s)
Adaptation, Physiological , Blood Pressure/physiology , Cardiovascular Physiological Phenomena , Heart/physiology , Hypertension/physiopathology , Reflex/physiology , Adult , Humans , MaleABSTRACT
The study determined the contribution of activity balance of the two motivational systems, i.e. appetitive and defensive, into mechanisms of blood pressure (BP) regulation in humans. Average age of participants was 30.29 +/- 9.8 years. Men having the BP within normal range and the individuals with firstly diagnosed increased arterial blood pressure up to abnormal values were selected. Using the method of emotional modulation of the startle reflex (EMSR) by different profiles of the EMSR. The participants with shifted balance toward enhanced activity of defensive system (amplified probe startle by unpleasant context) or shifted balance toward low activity of appetitive system (decrease or inhibition of the probe startle by pleasant context) had significantly increased BP in resting. Putative mechanisms of the revealed phenomena are discussed.
