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1.
Clin Chem ; 70(6): 786-788, 2024 Jun 03.
Article in English | MEDLINE | ID: mdl-38441566
3.
Yale J Biol Med ; 93(1): 45-47, 2020 03.
Article in English | MEDLINE | ID: mdl-32226335

ABSTRACT

Diltiazem is a calcium-channel blocker commonly used for the treatment of hypertension. Common adverse effects include dizziness, headache, and edema. Fewer than 20 cases of diltiazem-associated photodistributed hyperpigmentation have been reported in the literature. Here, we present the case of a 71-year-old woman with new-onset facial hyperpigmentation 6 months after initiating treatment with diltiazem.


Subject(s)
Diltiazem/adverse effects , Hyperpigmentation , Hypertension/drug therapy , Photosensitivity Disorders , Skin/pathology , Tacrolimus/pharmacology , Aged , Biopsy , Calcium Channel Blockers/administration & dosage , Calcium Channel Blockers/adverse effects , Dermatologic Agents/pharmacology , Diltiazem/administration & dosage , Female , Humans , Hyperpigmentation/chemically induced , Hyperpigmentation/pathology , Hyperpigmentation/therapy , Ointments , Photosensitivity Disorders/chemically induced , Photosensitivity Disorders/pathology , Photosensitivity Disorders/therapy , Treatment Outcome , Withholding Treatment
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