ABSTRACT
BACKGROUND: Bladder cancer occurs mainly in adults. In children, younger than 10 years in particular, it is very rare. OBJECTIVES: The aim of the study is to retrospectively evaluate the efficacy of transurethral resection of the bladder tumour (TUR-BT) of transitional cell carcinoma (TCC) of the bladder in children. MATERIAL AND METHODS: Transurethral resection of the bladder tumour was performed in 7 boys aged 4 to 17 years (median 12.1 years). In all cases laboratory tests, ultrasound, and cystoscopic tumour biopsy were carried out prior to the resection. Doxorubicin was additionally instilled intravesically as one dose in two patients. The Foley catheter was left in the bladder for 1 to 4 days (median 1.85 days). The follow-up period ranged from 10 months to 10 years (median 4 years). RESULTS: Papillary urothelial neoplasm of low malignant potential (PUNLMP) was diagnosed in 5 patients and urothelial papilloma in 2. Local recurrence was observed in one case two years after the resection. In all other cases complete remission was achieved. CONCLUSIONS: Transitional cell carcinoma of the bladder in children is usually benign and endoscopic treatment (TUR-BT) seems to be the treatment of choice. To determine a follow-up schedule a more substantial group of children with bladder cancer should be analysed.
Subject(s)
Carcinoma, Transitional Cell/surgery , Cystectomy/methods , Urinary Bladder Neoplasms/surgery , Administration, Intravesical , Adolescent , Age Factors , Antibiotics, Antineoplastic/administration & dosage , Carcinoma, Transitional Cell/pathology , Chemotherapy, Adjuvant , Child , Child, Preschool , Cystectomy/adverse effects , Doxorubicin/administration & dosage , Humans , Male , Neoplasm Recurrence, Local , Poland , Remission Induction , Retrospective Studies , Time Factors , Treatment Outcome , Urinary Bladder Neoplasms/pathologyABSTRACT
During the last decade more and more urodynamic studies in children have been performed as a step in diagnostic process of urinary tract diseases in children. Such a procedure is done to diagnose a cause of urinary tract infection as well. The aim of our study was to evaluate uroflowmetric parameters in children with urinary tract infections and try to find typical sings. Among the children examined at the Department as an out-patient we randomly selected the group of 379 patients. There were 94 patients afflicted with urinary tract infection without any special predisposing factors. The range of age was 5-15 years (ave--9.1, Me--9). There were 84 girls and 10 boys. A control group consisted of 195 patients in the range of age 5-16 years (ave 9.6). We analysed standard parameters of the uroflowmetric protocol (maximal and average flow, urinary bladder volume, residual volume, and time flow). Results were presented as average (X) and standard deviation (SD). There was no statistically significant difference between both group (p < 0.05).
