ABSTRACT
â¢This case reports the treatment of neuroendocrine carcinoma of the cervix with a PARPi based on NGS.â¢NGS reports have demonstrated somatic mutations BRCA in neuroendocrine carcinoma of the cervix.â¢The use of a PARPi in neuroendocrine carcinoma of the cervix has not been previously reported.
ABSTRACT
West Nile virus (WNV) infections are potentially life threatening in immunocompromised hosts. Currently, the best diagnostic test is serology. Reverse-transcriptase polymerase chain reaction (RT-PCR) testing has a role, but, because WNV is a cell-associated neurotropic virus, RT-PCR results are frequently negative even in cases of active infection. We present a case in which serology results were persistently negative because the patient was immunocompromised following lymphoma treatment. The role of humoral immunity in resolution of WNV is also discussed.
