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1.
Ann Dermatol Venereol ; 139(1): 50-3, 2012 Jan.
Article in French | MEDLINE | ID: mdl-22225743

ABSTRACT

INTRODUCTION: Cutaneous syringotropic T-cell lymphoma is a rare form of lymphoma. We report a case involving a misleading cutaneous presentation on the sole of the foot. PATIENTS AND METHODS: A 55-year-old woman presented discrete coalescent papules on her left foot, having an anhidrotic appearance, for which a number of antifungal treatments had been given without success. The skin biopsy revealed CD4+ T lymphocytic dermal infiltrate, mainly near the sweat glands, with syringotropism. The diagnosis of syringotropic T-cell lymphoma was reinforced by the presence of dominant cutaneous T-lymphocyte clone in the skin biopsy. Staging tests were negative. Treatment was initiated with an extremely potent (class IV) dermal corticosteroid. DISCUSSION: Syringotropic T-cell lymphoma is an extremely rare form of cutaneous lymphoma similar in presentation to mycosis fungoides, characterised by the mainly perisudoral and syringotropic nature of the lymphocytic infiltrate. The value of this case report lies in the extremely mild nature of the misleading skin lesions, which could only be diagnosed through biopsy. Treatment for this condition is not as yet codified due to the extremely low number of cases reported in the literature.


Subject(s)
Dermatomycoses/diagnosis , Diagnostic Errors , Foot Diseases/diagnosis , Mycosis Fungoides/diagnosis , Skin Neoplasms/diagnosis , Sweat Glands/pathology , Carmustine/therapeutic use , Clobetasol/therapeutic use , Female , Foot Diseases/chemically induced , Foot Diseases/drug therapy , Foot Diseases/pathology , Humans , Middle Aged , Mycosis Fungoides/chemically induced , Mycosis Fungoides/classification , Mycosis Fungoides/drug therapy , Mycosis Fungoides/pathology , Ointments/adverse effects , Skin Neoplasms/chemically induced , Skin Neoplasms/drug therapy , Skin Neoplasms/pathology
2.
Ann Dermatol Venereol ; 138(11): 736-8, 2011 Nov.
Article in French | MEDLINE | ID: mdl-22078033

ABSTRACT

BACKGROUND: Multiple cutaneous osteomas are a rare complication of chronic inflammatory acne that often goes unrecognized. We report a case concerning a 35-year-old woman. PATIENTS AND METHODS: A 35-year-old woman had been treated for acne since the age of 22 years, as part of which she received two courses of oral isotretinoin. We noted the secondary appearance of several microcysts on the face for which the excision was very difficult. Curiously, these small formations did not contain keratin but were very callous. Histological examination revealed foci of osseous metaplasia, probably of postinflammatory origin. Treatment consisted solely of excision of the lesions. DISCUSSION: Osteoma cutis comprises two distinct groups (primary and secondary). In our case, there were multiple cutaneous osteomas of the face resulting from chronic acne. The differential diagnosis was idiopathic miliary osteomatosis of the face, but this was ruled out by the young age of the patient, the improvement of the acneiform lesions under isotretinoin (confirming the initial diagnosis of acne) and the subsequent appearance of microcysts. Although there are as yet no codified treatments, excision appears to yield good results.


Subject(s)
Acne Vulgaris/complications , Neoplasms, Multiple Primary/etiology , Osteoma/etiology , Skin Neoplasms/etiology , Acne Vulgaris/drug therapy , Adult , Anti-Bacterial Agents/therapeutic use , Dermatologic Agents/therapeutic use , Durapatite/analysis , Female , Fenofibrate/therapeutic use , Humans , Hypertriglyceridemia/complications , Hypertriglyceridemia/drug therapy , Hypolipidemic Agents/therapeutic use , Isotretinoin/therapeutic use , Minocycline/therapeutic use , Neoplasms, Multiple Primary/chemistry , Neoplasms, Multiple Primary/surgery , Osteoma/chemistry , Osteoma/surgery , Skin Neoplasms/chemistry , Skin Neoplasms/surgery
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