[Maximal and minimal lung resection in cancer of the lung]. / Maksimal'no-minimal'nye rezektsii pri rake legkikh.

The results of segmental pulmonary resections in 146 patients with lung cancer were analysed. The surgical results were found to be related to the extension of the process, histological pattern, the extent of tumor differentiation and mode of postoperative treatment. The best results of segmental resections were seen in patients with differentiated forms of squamous cell and glandular carcinomas of the lung (T1NoMo). All patients of the present group were alive 3 years after resection, but the 5-year survival rate was 83.3%. The postoperative radiotherapy (40-45 Gr.) was performed in 65 patients. The postoperative radiotherapy improved the 5-year survival rates from 17.3% to 55.5%. The indications for segmental resections in lung cancer were defined.

[The early detection of stomach and lung cancer during the dispensary care of the population]. / Rannee vyiavlenie raka zheludka i legkogo pri dispanserizatsii naseleniia.

The system of early detection of cancer of the stomach and lung was developed on the basis of two-stage automated screening which involved questionnaires, instrumental and laboratory examination, and formation of high-risk and follow-up groups. Gastric and lung cancer were diagnosed in 1.5 and 1.3% of cases of high-risk groups, respectively. Stage I-II tumors made 80.8% of gastric cancer and 20.7% of lung malignancies. In the follow-up groups, all gastric tumors and half of lung neoplasms were diagnosed at early stages. The procedure described assures lower percentage of advanced tumors of the stomach and lung at diagnosis.

[The determination of the level of antibodies to Epstein-Barr virus antigens in organizing groups at high risk for lung cancer disease]. / Opredelenie urovnia antitel k antigenam virusa Epstaina--Bar pri formirovanii grupp povyshennogo riska zabolevaniia rakom legkogo.

Titers of antibodies against Epstein-Barr virus (EBV) antigen were measured in 450 subjects aged 40 years and older. The group included patients with lung cancer, cases of non-specific chronic lung pathology and healthy subjects (150 persons in each subset). A significant increase in the level of antibodies to capsid EBV antigen was established in patients with lung cancer and chronic non-specific lung pathology as compared to healthy controls. Parameters of specific immunologic response to Epstein-Barr virus may be recommended as additional criteria for inclusion into the group at risk for lung cancer.

[Main indicators of hormonal status in lung diseases]. / Osnovnye pokazateli gormonal'nogo statusa pri zabolevaniiakh legkikh.

A radioimmunoassay was used in vitro in the blood serum of 156 lung cancer patients, 21 patients with benign pulmonary tumors and 100 patients with chronic nonspecific pulmonary diseases to study the levels of 9 hormones reflecting function of the major links of endocrine regulation. The most important feature of pulmonary tumor growth was the activation of the hypophyseal-adrenal system. Endocrine shifts in lung cancer and in chronic nonspecific pulmonary diseases were similar in nature. Of the entire spectrum of hormones the importance of ACTH, cortisol, calcitonin and parathyroid hormone was emphasized in differential diagnosis of lung cancer.

[Endarterectomy of the femoral and popliteal arteries]. / Endarteréktomiia bedrennykh i podkolennykh arterii.

The experience of 127 operations for endarterectomy of occlusions of the femoral and popliteal arteries in 122 patients is analyzed. The remote results were observed for 10 years. The cumulative analysis within 10 years after operations have shown 27% of endarectomized arteries to remain passable. The best results were obtained when using the gaseous method modified by the authors, for correction of short occlusions in combination with good outflow pathways. With this form of pathology 68% of arteries are found to be passable within 10 postoperative years.