ABSTRACT
Cholestasis has numerous causes. We present the case of a 78-year-old man with a common diagnosis in this age group and gender but with an unusual presentation. There are only 11 articles published of patients with jaundice due to a paraneoplastic syndrome associated with prostate cancer. Interleukin 6 and other proinflammatory cytokines appear to contribute to the pathophysiology of this syndrome. Our patient remains symptom free 4 months after treatment initiation.
Subject(s)
Anilides/administration & dosage , Jaundice/etiology , Nitriles/administration & dosage , Paraneoplastic Syndromes/diagnosis , Prostatic Neoplasms/diagnosis , Tosyl Compounds/administration & dosage , Aged , Anilides/therapeutic use , Humans , Male , Neoplasm Metastasis , Nitriles/therapeutic use , Paraneoplastic Syndromes/drug therapy , Prostatic Neoplasms/drug therapy , Tosyl Compounds/therapeutic use , Treatment OutcomeABSTRACT
A patient with acute respiratory infection and severe hyponatraemia was admitted to our department. The hyponatraemia study was compatible with syndrome of inappropriate antidiuresis (SIAD) and an association with the respiratory problem was initially assumed. The recurrence of hyponatraemia after resolution of the pulmonary infection led to further investigation and to the diagnosis of tuberculous lymphadenitis. After treatment of this condition, discontinuation of SIAD treatment was possible, making this association presumable. We would like to highlight the importance of considering alternative conditions in the approach to SIAD.
Subject(s)
Haemophilus Infections/complications , Haemophilus influenzae , Inappropriate ADH Syndrome/complications , Inappropriate ADH Syndrome/diagnosis , Tuberculosis, Lymph Node/complications , Tuberculosis, Lymph Node/diagnosis , Aged , Cough/microbiology , Dyspnea/microbiology , Female , Haemophilus Infections/drug therapy , Humans , Inappropriate ADH Syndrome/drug therapy , Respiratory Tract Infections/diagnosis , Respiratory Tract Infections/drug therapy , Respiratory Tract Infections/microbiology , Tuberculosis, Lymph Node/drug therapyABSTRACT
We report a case of a 74-year-old man who presented to the emergency department with a 1-week history of fever. He had a meatal stenosis and had a suprapubic catheter for 10â months, and had a recent hospitalisation for urosepsis with bacteraemia due to methicillin-resistant Staphylococcus aureus after manipulation of the catheter. Clinical examinations were performed in the emergency department and the patient was hospitalised with the diagnosis of recurrent urinary tract infection. The following day, we noticed the development of a mass in the left sternoclavicular joint with inflammatory signs and excruciating pain. Ultrasonographic findings led to the diagnosis of left sternoclavicular synovitis, and methicillin-resistant S. aureus grew in blood cultures leading to the diagnosis of sternoclavicular septic arthritis. Treatment with vancomycin and gentamicin was started and maintained for 4â weeks with complete resolution of symptoms and no complications or sequelae.
