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Mutat Res ; 658(3): 154-61, 2008.
Article in English | MEDLINE | ID: mdl-17827055

ABSTRACT

The polysaccharides beta-glucans occur as a principal component of the cellular walls. Some microorganisms, such as yeast and mushrooms, and also cereals such as oats and barley, are of economic interest because they contain large amounts of beta-glucans. These substances stimulate the immune system, modulating humoral and cellular immunity, and thereby have beneficial effect in fighting infections (bacterial, viral, fungal and parasitic). beta-Glucans also exhibit hypocholesterolemic and anticoagulant properties. Recently, they have been demonstrated to be anti-cytotoxic, antimutagenic and anti-tumorogenic, making them promising candidate as pharmacological promoters of health.


Subject(s)
Mutation/drug effects , Neoplasms/prevention & control , beta-Glucans/therapeutic use , Animals , Anti-Infective Agents/chemistry , Anti-Infective Agents/isolation & purification , Anti-Infective Agents/pharmacology , Anti-Infective Agents/therapeutic use , Antimutagenic Agents/chemistry , Antimutagenic Agents/isolation & purification , Antimutagenic Agents/pharmacology , Antimutagenic Agents/therapeutic use , Antineoplastic Agents/chemistry , Antineoplastic Agents/isolation & purification , Antineoplastic Agents/pharmacology , Antineoplastic Agents/therapeutic use , Cytoprotection/drug effects , Cytoprotection/genetics , Health Promotion/methods , Humans , Models, Biological , Neoplasms/genetics , beta-Glucans/chemistry , beta-Glucans/isolation & purification , beta-Glucans/pharmacology
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