Subject(s)
Humans , Skin Neoplasms/epidemiology , Melanoma/epidemiology , Prognosis , Sex Factors , Retrospective StudiesABSTRACT
Abstract Muir-Torre syndrome is a rare, autosomal dominant genodermatosis, characterized by sebaceous neoplasms and visceral carcinomas. The authors describe the case of a patient who, 16 years after the diagnosis of colon carcinoma, presented a verrucous plaque on the pubic region, histopathologically compatible with sebaceous adenoma. The need to investigate this syndrome is emphasized, especially in cases of sebaceous neoplasms located outside the head, face, and neck. Screening for neoplasms in these patients and their families is mandatory.
Subject(s)
Humans , Sebaceous Gland Neoplasms , Carcinoma , Adenoma , Colonic Neoplasms , Muir-Torre SyndromeABSTRACT
Muir-Torre syndrome is a rare, autosomal dominant genodermatosis, characterized by sebaceous neoplasms and visceral carcinomas. The authors describe the case of a patient who, 16 years after the diagnosis of colon carcinoma, presented a verrucous plaque on the pubic region, histopathologically compatible with sebaceous adenoma. The need to investigate this syndrome is emphasized, especially in cases of sebaceous neoplasms located outside the head, face, and neck. Screening for neoplasms in these patients and their families is mandatory.
Subject(s)
Adenoma , Carcinoma , Colonic Neoplasms , Muir-Torre Syndrome , Sebaceous Gland Neoplasms , HumansABSTRACT
OBJECTIVE: The relationship between the clinicopathological and sociodemographics characteristics of acral melanomas diagnosed at the Hospital do Servidor Público Estadual de São Paulo was analyzed and traced between 1997 and 2016. METHODS: An observational, descriptive, and retrospective study of patients diagnosed with acral melanoma was performed at Hospital do Servidor Público Estadual de São Paulo. Sociodemographic and clinicopathological characteristics were collected and analyzed. RESULTS: Forty-five patients with acral melanomas were found during the evaluation period. Thirty-one were females, and 14 were males (68.89% and 31.3%, respectively). Most of the cases were invasive (88.37%), and the predominant histological subtype was the acral lentiginous (91.11%). The plantar region was the most prevalent (64.44%). The median Breslow index was 3 mm, and there was a tendency towards greater severity in male patients. CONCLUSIONS: Acral site melanomas are detected diagnosed when they reach more advanced stages, which leads to a worse prognosis for patients. Late detection assumes even greater importance in highly mixed and black populations, such as the Brazilian population.
Subject(s)
Melanoma , Skin Neoplasms , Brazil/epidemiology , Female , Humans , Male , Melanoma/epidemiology , Prognosis , Retrospective Studies , Skin Neoplasms/epidemiologyABSTRACT
Abstract The authors report a case of mobile and painful nodules on the bilateral plantar surface of a female patient referred by the rheumatology service, where she was being followed-up for rheumatoid arthritis. A nodule excision was performed for differential diagnosis and symptom relief; the histopathological analysis was compatible with a rheumatoid nodule. Although rheumatoid nodules are a common manifestation of rheumatoid arthritis, exclusive plantar involvement is seldom described in the literature.
Subject(s)
Humans , Female , Arthritis, Rheumatoid/diagnosis , Rheumatoid Nodule/diagnosis , Pain , Diagnosis, DifferentialSubject(s)
Coronavirus Infections/diagnosis , Coronavirus/isolation & purification , Exanthema , Pneumonia, Viral/diagnosis , Purpura/virology , Adult , Betacoronavirus , COVID-19 , Coronavirus Infections/complications , Humans , Leg , Male , Pandemics , Pneumonia, Viral/complications , Purpura/diagnosis , SARS-CoV-2ABSTRACT
The authors report a case of mobile and painful nodules on the bilateral plantar surface of a female patient referred by the rheumatology service, where she was being followed-up for rheumatoid arthritis. A nodule excision was performed for differential diagnosis and symptom relief; the histopathological analysis was compatible with a rheumatoid nodule. Although rheumatoid nodules are a common manifestation of rheumatoid arthritis, exclusive plantar involvement is seldom described in the literature.
