ABSTRACT
Coxiella burnetii is the agent of Q fever, a disease that poses risks to public health and damages livestock. We discovered the circulation of C. burnetii for the first time in Paraguay, based on the seropositivity of a flock of >300 sheep. The animals were tested by IFA for anti-C. burnetii antibodies and by SAM for anti-Leptospira spp. antibodies, an important differential diagnosis for reproductive disorders in sheep in Paraguay. C. burnetii seropositivity was determined in 45%, in contrast to Leptospira spp. which had no reactive samples. Cases of miscarriage and fetal resorption were associated with high seropositivity titers. This study suggests the circulation of a unique genotype in the country and an imminent risk to public health, since in addition to being highly transmissible and infectious to humans, Q fever is still not a cause for concern on the part of government and health agencies in the country.
ABSTRACT
O linfoma anaplásico de células grandes (ALCL) associado a implantes mamários é um distúrbio ainda pouco descrito na literatura, porém o número de casos está crescendo rapidamente. Das poucas centenas de casos que foram publicados até agora, poucos são de pacientes brasileiras. Analisando os dados obtidos, notou-se que o linfoma anaplásico de grandes células se apresenta com dor mamária, derrame periprotético, massa palpável, dentre outras características. Em vista destes aspectos, conclui-se que uma boa investigação deve ser realizada ao surgirem sintomas inespecíficos, independentemente do tempo que a cirurgia foi realizada, uma vez que estas complicações podem ocorrer anos após a cirurgia. O prognóstico é muito bom na maior parte dos casos diagnosticados. No entanto, apesar de algumas teorias, não se concluiu com exatidão, ainda, como e por que os implantes de silicone poderiam desencadear uma resposta linfóide, culminando num ALCL
Anaplastic large cell lymphoma (ALCL) associated with breast implants is a disorder still poorly described in the literature, but the number of cases is rapidly increasing. Of the few hundred cases that have been published so far, few are from Brazilian patients. Analyzing the data obtained, it was noted that anaplastic large cell lymphoma presents with breast pain, periprosthetic effusion, palpable mass, among other characteristics. In view of these aspects, it is concluded that a thorough investigation should be carried out when nonspecific symptoms arise, regardless of the time the surgery was performed, since these complications can occur years after surgery. The prognosis is very good in most diagnosed cases. However, despite some theories, it has not yet been conclusively determined how and why silicone implants could trigger a lymphoid response, culminating in ALCL
