1.
Inorg Chem
; 50(21): 10519-21, 2011 Nov 07.
Article
in English
| MEDLINE
| ID: mdl-21970295
ABSTRACT
In this report, we demonstrate how UV-light exposure can enhance DNA cleavage promoted by two copper(II) complexes of tetracyclines and 1,10-phenanthroline about 40 times in comparison to nonirradiated conditions. In addition, new aspects regarding their DNA binding properties, as well as the mechanism of the cleavage reaction, were also investigated.