ABSTRACT
Clear cell acanthoma is an uncommon type of benign epithelial tumor. Typically, it is a solitary lesion found on the lower limbs. It presents as a nodule or small plaque with slow and well-defined growth. Diagnosis used to be clinical and histopathological, but the advent of dermoscopy has led to an increase in diagnostic accuracy. We describe a case in which dermoscopy proved highly useful for diagnosis of the lesion.
Subject(s)
Acanthoma/diagnosis , Dermoscopy , Leg , Skin Neoplasms/diagnosis , Acanthoma/pathology , Diagnosis, Differential , Humans , Male , Middle Aged , Skin Neoplasms/pathologyABSTRACT
Abstract: Clear cell acanthoma is an uncommon type of benign epithelial tumor. Typically, it is a solitary lesion found on the lower limbs. It presents as a nodule or small plaque with slow and well-defined growth. Diagnosis used to be clinical and histopathological, but the advent of dermoscopy has led to an increase in diagnostic accuracy. We describe a case in which dermoscopy proved highly useful for diagnosis of the lesion.
Subject(s)
Humans , Male , Middle Aged , Skin Neoplasms/diagnosis , Acanthoma/diagnosis , Dermoscopy , Skin Neoplasms/pathology , Acanthoma/pathology , Diagnosis, Differential , LegABSTRACT
Annular elastolytic giant cell granuloma (AEGCG) is a rare granulomatous skin disease of unclear pathogenesis which belongs to the group of disorders in the skin and elastic fibers with similar clinical features of granuloma annulare (GA). This case report is intended to describe a rare hybrid pattern in histopathology demonstrating coexistence of AEGCG and GA. An endocrine disease, such as diabetes mellitus (DM), could contribute to the coexistence of both lesions, and this possibility must be included in the medical investigation.
ABSTRACT
Hepatitis C virus has been associated with various skin conditions, such as porphyria cutanea tarda and lichen planus, as an example. The objective of this paper is based on the description of a case of localized morphea, which came years after the discovery of hepatitis C, as well as a discussion of possible relations between both diseases.
ABSTRACT
JUSTIFICATIVA E OBJETIVOS: Na última metade do século XX, o advento da penicilina e a maior atenção às iniciativas que visam prevenção das doenças sexualmente transmissíveis representaram um grande avanço no combate à sífilis. No entanto, a sua prevalência no Brasil ainda é elevada e constitui um importante problema de saúde pública. O objetivo deste estudo foi relatar a apresentação da variedade das manifestações clínicas da sífilis secundária, incluindo formas incomuns e reflexos de sua associação com o vírus da imunodeficiência humana (HIV). RELATO DOS CASOS: São apresentados e discutidos quatro casos de lues secundária tratados com penicilina benzatina, sendo cada um com clínica peculiar: lesões palmo-plantares em conjunto com pápulas disseminadas pelo corpo, sifilides elegantes, sífilis maligna precoce e alopécia. Sintomatologia sistêmica também é discutida quando presente, assim como a relação entre a coinfecção com o HIV e provas laboratoriais. CONCLUSÃO: Observou-se neste estudo a capacidade de polimorfismo das lesões dermatológicas da sífilis secundária reforçando a expressão que a doença recebe de "o grande imitador" e destaca a necessidade de refamiliarização para com as diversas formas clínicas do secundarismo das lues.
BACKGROUND AND OBJECTIVES: In the last half of 20th century, the advent of penicillin and more attention to initiatives aimed at prevention of sexually transmitted diseases represent a major breakthrough in the fight against syphilis. However, the prevalence of syphilis in Brazil is still high and so it is an important public health problem. The main purpose of these reports is the presentation of the variety of clinical manifestations of secondary syphilis, including unusual presentations and aspects of its association with human immunodeficiency virus (HIV). CASE REPORTS: Presented and discussed four cases of secondary syphilis treated with penicillin G benzathine, each with thefollowings presentations: palmoplantar papules and disseminated lesions, syphilids elegant, early malignant syphilis and alopecia. Systemic symptoms when present are also discussed, as well as the relationship between co-infection with HIV and laboratory tests. CONCLUSION: The study reflects the polymorphism of the skin lesions of secondary syphilis enhancing the expression that the disease was "the great imitator" and highlights the need to re-familiarization with the various forms of secondary syphilis.
Subject(s)
Humans , Male , Female , Adult , Acquired Immunodeficiency Syndrome , Syphilis , Sexually Transmitted DiseasesABSTRACT
Foi realizada extensa revisão acerca do tema necrólise epidérmica tóxica e síndrome de Stevens Johnson, reunindo-se notável gama de informações no que se refere a manifestações clínicas, diagnóstico e técnicas recentes de tratamento. Ao final desta pesquisa de aprofundamento clínico e aprendizado, os autores visam o oferecimento de conhecimento sobre essas raras e graves manifestações comuns em centros de terapia de grandes queimados, destacando o papel desses locais na avaliação médica multidisciplinar de tais pacientes, assim como tratamento e suporte rápido à vida.
Review article of toxic epidermal necrolysis and Stevens-Johnson syndrome flocking remarkable range of information regarding the clinical, diagnosis and recent treatment techniques. The authors aim, at the end of this further research and clinical learning, offer knowledge about these rare and severe manifestations common in centers of large burns therapy, highlighting the role of local multidisciplinary medical evaluation of such patients, as well as treatment and support.
Subject(s)
Humans , Burn Units , Drug-Related Side Effects and Adverse ReactionsABSTRACT
Injectable polymethylmethacrylate (PMMA) microspheres are nonbiodegradable and too large for macrophage phagocytosis. There are several complications possible to happen, like chronic nonspecific inflammatory reactions, lip stiffness, infection, and granulomas. The occurrence of granulomas can lead to a not aesthetic result, making some extreme changes in the patient's life. The objective of this case report is to describe the successful treatment of foreign body granulomas caused by polymethylmethacrylate microspheres using allopurinol, an innovative therapy for this condition.
