ABSTRACT
Over the past several years, the epidemiological profile of dengue has been changing progressively and is currently characterized by an increase in the number of cases in children under 15 years of age. This study was aimed at comparing the clinical and laboratory features between adults and children with dengue; therefore, we performed a cross-sectional analysis of 5686 individuals with laboratory-confirmed dengue who sought treatment at a healthcare facility in Rio de Janeiro, Brazil from 2010 to 2011. A multivariate analysis indicated that myalgia (OR = 2.58; CI 95% = 2.08-3.18), retro-orbital pain (OR = 1.36; CI 95% = 1.15-1.62), nausea (OR = 1.92; CI 95% = 1.60-2.30), and arthralgia (OR = 3.64; CI 95% = 2.72-4.89) were the most frequent clinical symptoms in adults, whereas vomiting (OR = 0.52; CI 95% = 0.43-0.61) and skin rash (OR = 0.46; CI 95% = 0.25-0.85) were the most prevalent symptoms in children. Adults exhibited a higher hemoconcentration (OR = 3.04; CI 95% = 2.53-3.65), thrombocytopenia (OR = 2.17; CI 95% = 1.80-2.60), increased erythrocyte sedimentation rate (OR = 1.81; CI 95% = 1.53-2.14), and increased ALT (OR = 3.13; CI 95% = 2.44-4.02) than did children. In addition, adults exhibited a higher frequency of the severe forms of the disease (OR = 1.74; CI 95% = 1.12-2.72) and hospitalization (OR = 2.21; CI 95% = 1.59-3.06) relative to children. Based on these results, this study demonstrated significant differences in the clinical and laboratory presentations and disease severity between adults and children affected by dengue.
Subject(s)
Adolescent , Adult , Child , Child, Preschool , Female , Humans , Infant , Infant, Newborn , Male , Dengue/diagnosis , Age Factors , Brazil/epidemiology , Cross-Sectional Studies , Dengue/complications , Dengue/epidemiology , Multivariate Analysis , Severity of Illness IndexABSTRACT
Over the past several years, the epidemiological profile of dengue has been changing progressively and is currently characterized by an increase in the number of cases in children under 15 years of age. This study was aimed at comparing the clinical and laboratory features between adults and children with dengue; therefore, we performed a cross-sectional analysis of 5686 individuals with laboratory-confirmed dengue who sought treatment at a healthcare facility in Rio de Janeiro, Brazil from 2010 to 2011. A multivariate analysis indicated that myalgia (OR=2.58; CI 95%=2.08-3.18), retro-orbital pain (OR=1.36; CI 95%=1.15-1.62), nausea (OR=1.92; CI 95%=1.60-2.30), and arthralgia (OR=3.64; CI 95%=2.72-4.89) were the most frequent clinical symptoms in adults, whereas vomiting (OR=0.52; CI 95%=0.43-0.61) and skin rash (OR=0.46; CI 95%=0.25-0.85) were the most prevalent symptoms in children. Adults exhibited a higher hemoconcentration (OR=3.04; CI 95%=2.53-3.65), thrombocytopenia (OR=2.17; CI 95%=1.80-2.60), increased erythrocyte sedimentation rate (OR=1.81; CI 95%=1.53-2.14), and increased ALT (OR=3.13; CI 95%=2.44-4.02) than did children. In addition, adults exhibited a higher frequency of the severe forms of the disease (OR=1.74; CI 95%=1.12-2.72) and hospitalization (OR=2.21; CI 95%=1.59-3.06) relative to children. Based on these results, this study demonstrated significant differences in the clinical and laboratory presentations and disease severity between adults and children affected by dengue.
Subject(s)
Dengue/diagnosis , Adolescent , Adult , Age Factors , Brazil/epidemiology , Child , Child, Preschool , Cross-Sectional Studies , Dengue/complications , Dengue/epidemiology , Female , Humans , Infant , Infant, Newborn , Male , Multivariate Analysis , Severity of Illness IndexABSTRACT
As transformações sociodemográficas pelas quais o Brasil vem passando têm causado mudanças relevantes no perfilde morbi-mortalidade, tornando o câncer um problema de Saúde Pública. São estimados, em 2010, 489.270 novoscasos no Brasil. O conhecimento dos fatores associados ao câncer é fundamental para o estabelecimento de práticas de promoção à saúde e prevenção do câncer. Este estudo tem como objetivo conhecer a prevalência de fatores associados ao câncer entre os alunos de graduação na área da saúde e de ciências biológicas. Foi realizado um estudo transversal e descritivo em participantes do II Curso de Verão de Pesquisa em Oncologia do INCA. Foram coletados dados relativos às variáveis sociodemográficas, exposição a fatores associados ao câncer e cuidados com a saúde. Os participantes assinaram o termo de consentimento livre e esclarecido e o estudo seguiu as normas da resolução 196/96. A populaçãofoi composta por 75% de mulheres. Dentre os fatores de risco conhecidos para o desenvolvimento do câncer, encontrouse a prevalência de: 2,5% tabagistas; 12,5% consumo de risco de bebidas alcoólicas; 51,3% sedentários; 51,3% baixo consumo de frutas; 40,0% baixo consumo de legumes; 60,0% baixo consumo de verduras; 7,5% exposição solar sem o uso de protetor ou filtro; e 5,1% sobrepeso. A prevalência elevada de alguns fatores aponta para a necessidade daimplementação de políticas de prevenção e promoção à saúde com o objetivo de se reduzir a exposição dos acadêmicos da área da saúde e de ciências biológicas aos fatores associados ao câncer
