Subject(s)
Antibodies, Monoclonal, Humanized/therapeutic use , Antineoplastic Agents, Immunological/therapeutic use , Epstein-Barr Virus Infections/complications , Plasmablastic Lymphoma/drug therapy , Plasmablastic Lymphoma/radiotherapy , Aged , HIV Infections/complications , Herpesvirus 4, Human/isolation & purification , Humans , Male , Plasmablastic Lymphoma/complications , Treatment OutcomeSubject(s)
Fibromatosis, Aggressive/pathology , Gastrointestinal Neoplasms/pathology , Gastrointestinal Stromal Tumors/pathology , Neoplasm Recurrence, Local/pathology , Diagnosis, Differential , Gastrointestinal Neoplasms/diagnosis , Gastrointestinal Neoplasms/therapy , Gastrointestinal Stromal Tumors/diagnosis , Gastrointestinal Stromal Tumors/therapy , Humans , Male , Middle Aged , Neoplasm Recurrence, Local/diagnosis , Retrospective StudiesABSTRACT
There are numerous materials that are used as temporaries for inlay and onlay preparations while the permanent restoration is being made. This article looks at 2 types of temporary materials that were placed into inlay or onlay preparations by student dentists: a methylmethacrylate acrylic material (DuraLay Inlay Pattern Resin) and a visible light-cured (VLC) periodontal surgical dressing (Barricaid). The resilience and effectiveness of both products are compared and evaluated for use as temporary restorations in inlay or onlay preparations. The study found that use of the VLC periodontal dressing material offers a novel technique for a quick and efficient method to provide a temporary restoration for various inlay and onlay preparations.
Subject(s)
Dental Materials/chemistry , Dental Restoration, Temporary/methods , Inlays , Methylmethacrylates/chemistry , Periodontal Dressings , Resins, Synthetic/chemistry , Cementation/methods , Dental Cavity Preparation/methods , Dental Marginal Adaptation , Dental Prosthesis Repair , Dental Prosthesis Retention , Dental Restoration Failure , Dentistry, Operative/education , Follow-Up Studies , Gingiva/pathology , Humans , Periodontal Index , Students, Dental , Time FactorsABSTRACT
When faced with the presence of peg laterals in adolescent patients, the problem is, how do you correct the laterals in order to obtain an esthetic smile result? This case study describes a procedure to produce an esthetic smile for an adolescent patient. The procedure represented in this case report is only a temporary way to create an esthetic smile until the patient becomes an adult, when a more permanent solution addressing the peg laterals can be accomplished.
Subject(s)
Incisor/abnormalities , Patient Care Team , Adolescent , Dental Prosthesis Design , Dental Restoration, Temporary , Dental Veneers , Esthetics, Dental , Female , Humans , Malocclusion, Angle Class II/therapy , Orthodontic Retainers , Palatal Expansion Technique , Tooth Movement TechniquesABSTRACT
When faced with the need for emergency replacement of anterior teeth, the problem for dentists and their patients is how can lost teeth be replaced quickly? Laboratory-fabricated replacement appliances require significant time and expense, not to mention an extended period, during which the patient remains edentulous. This report describes a procedure to construct an immediate, low-cost replacement for one or more missing anterior teeth-one that requires no laboratory time. The resulting appliance is meant only as a stop gap and does not support chewing; but it does offer an esthetically pleasing, removable prosthesis that provides phonetic and lip support during the short time necessary to fabricate and place a permanent prosthesis.
Subject(s)
Denture Design , Denture, Partial, Immediate , Denture, Partial, Temporary , Incisor , Tooth Loss/therapy , Acrylic Resins , Adult , Humans , Male , Maxilla , Middle Aged , Models, Dental , Tooth, ArtificialABSTRACT
An improved Raman gain spectrometer for flame measurements of gas temperature and species concentrations is described. This instrument uses a multiple-pass optical cell to enhance the incident light intensity in the measurement volume. The Raman signal is 83 times larger than from a single pass, and the Raman signal-to-noise ratio (SNR) in room-temperature air of 153 is an improvement over that from a single-pass cell by a factor of 9.3 when the cell is operated with 100 passes and the signal is integrated over 20 laser shots. The SNR improvement with the multipass cell is even higher for flame measurements at atmospheric pressure, because detector readout noise is more significant for single-pass measurements when the gas density is lower. Raman scattering is collected and dispersed in a spectrograph with a transmission grating and recorded with a fast gated CCD array detector to help eliminate flame interferences. The instrument is used to record spontaneous Raman spectra from N(2), CO(2), O(2), and CO in a methane-air flame. Curve fits of the recorded Raman spectra to detailed simulations of nitrogen spectra are used to determine the flame temperature from the shapes of the spectral signatures and from the ratio of the total intensities of the Stokes and anti-Stokes signals. The temperatures measured are in good agreement with radiation-corrected thermocouple measurements for a range of equivalence ratios.
Subject(s)
Chromosome Deletion , Chromosomes, Human, Pair 5 , Myeloproliferative Disorders/genetics , Myeloproliferative Disorders/pathology , Polycythemia Vera/pathology , Aged , Antineoplastic Agents/therapeutic use , Chromosomes, Human, Pair 5/genetics , Disease Progression , Drug Resistance, Neoplasm/genetics , Drug Resistance, Neoplasm/physiology , Female , Humans , Lenalidomide , Myeloproliferative Disorders/complications , Myeloproliferative Disorders/drug therapy , Neoplasms/drug therapy , Neoplasms/genetics , Neoplasms/pathology , Philadelphia Chromosome , Polycythemia Vera/diagnosis , Polycythemia Vera/genetics , Splenomegaly/complications , Splenomegaly/pathology , Thalidomide/analogs & derivatives , Thalidomide/therapeutic useABSTRACT
Reports suggest reasonable efficacy and minimal myelosuppression from combination imatinib and hydroxyurea for recurrent malignant glioma. We retrospectively reviewed 16 patients treated with this regimen who were evaluable for toxicity; 14 were also evaluable for response. The incidence of grade 3-4 hematologic toxicity was 25%. The best radiographic response, by Macdonald criteria, was partial response (PR) in three patients (21%), stable disease (SD) in four (29%), and progressive disease (PD) in seven (50%). One patient with a PR developed therapy-limiting hematologic toxicity on day 19 of treatment, progressing to grade 4 on day 64, and persisting until death on day 127 despite discontinuing both drugs. Another patient with PR and two of four patients with SD also developed grade 3 hematologic toxicity. All patients with grade 3-4 hematologic toxicity had disease control (PR or SD) as best radiographic response, whereas none with PD suffered grade 3-4 hematologic toxicity. Combining imatinib with hydroxyurea is effective in some patients with malignant glioma. However, myelosuppression can persist for months after discontinuing the regimen, precluding further chemotherapy. Disease control may also correlate with hematologic toxicity (p = 0.08), suggesting that glioma and marrow stem cells may share a common sensitivity to this chemotherapy regimen.
Subject(s)
Antineoplastic Combined Chemotherapy Protocols/adverse effects , Bone Marrow Diseases/chemically induced , Brain Neoplasms/drug therapy , Glioblastoma/drug therapy , Neoplasm Recurrence, Local/drug therapy , Adult , Aged , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Benzamides , Bone Marrow/drug effects , Bone Marrow Diseases/complications , Brain Neoplasms/complications , Glioblastoma/complications , Humans , Hydroxyurea/administration & dosage , Imatinib Mesylate , Male , Middle Aged , Nucleic Acid Synthesis Inhibitors/administration & dosage , Piperazines/administration & dosage , Protein Kinase Inhibitors/administration & dosage , Protein-Tyrosine Kinases/antagonists & inhibitors , Pyrimidines/administration & dosage , Retrospective Studies , Treatment OutcomeABSTRACT
Multiple-pass optical cells with dense spot patterns are useful for many applications, especially when the cell volume must be minimized relative to the optical path length. Present methods to achieve these dense patterns require expensive, highly precise astigmatic mirrors and complex alignment procedures. This work describes a new, simpler, and less demanding mirror system, comprising either a pair of cylindrical mirrors or one cylindrical and one spherical mirror.
