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1.
Pediatr Neurol ; 23(2): 114-25, 2000 Aug.
Article in English | MEDLINE | ID: mdl-11020636

ABSTRACT

We studied 26 infants (1-18 months old) and 27 children (18 months or older) with acute nonaccidental (n = 21) or other forms (n = 32) of traumatic brain injury using clinical rating scales, a 15-point MRI scoring system, and occipital gray matter short-echo proton MRS. We compared the differences between the acutely determined variables (metabolite ratios and the presence of lactate) and 6- to 12-month outcomes. The metabolite ratios were abnormal (lower NAA/Cre or NAA/Cho; higher Cho/Cre) in patients with a poor outcome. Lactate was evident in 91% of infants and 80% of children with poor outcomes; none of the patients with a good outcome had lactate. At best, the clinical variables alone predicted the outcome in 77% of infants and 86% of children, and lactate alone predicted the outcome in 96% of infants and 96% of children. No further improvement in outcome prediction was observed when the lactate variable was combined with MRI ratios or clinical variables. The findings of spectral sampling in areas of brain not directly injured reflected the effects of global metabolic changes. Proton MRS provides objective data early after traumatic brain injury that can improve the ability to predict long-term neurologic outcome.


Subject(s)
Aspartic Acid/analogs & derivatives , Head Injuries, Closed/diagnosis , Lactic Acid/metabolism , Magnetic Resonance Imaging , Magnetic Resonance Spectroscopy , Aspartic Acid/metabolism , Brain Edema/diagnosis , Chi-Square Distribution , Child , Child, Preschool , Discriminant Analysis , Electroencephalography , Female , Humans , Infant , Infant, Newborn , Male , Predictive Value of Tests , Prognosis
2.
Pediatr Radiol ; 27(9): 760-2, 1997 Sep.
Article in English | MEDLINE | ID: mdl-9285742

ABSTRACT

We report a case of a 4-year-old boy with tetralogy of Fallot, pulmonary atresia, and hypoplastic pulmonary arteries who presented with mild hemoptysis and upper respiratory infection 3 weeks following percutaneous transluminal angioplasty for pulmonary artery stenosis. While pneumonia was initially suggested on early plain radiographs of the chest, a large pseudoaneurysm of a right lower lobe pulmonary artery branch was subsequently diagnosed with CT and angiography.


Subject(s)
Aneurysm, False/diagnostic imaging , Angioplasty, Balloon, Coronary/adverse effects , Pulmonary Artery/diagnostic imaging , Pulmonary Artery/injuries , Aneurysm, False/etiology , Child, Preschool , Diagnosis, Differential , Humans , Male , Pneumonia/diagnostic imaging , Tomography, X-Ray Computed
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