[Efficacy of prostaglandin E1 and systemic antibacterial therapy application in patients with diabetes mellitus and purulent-necrotic lesions of the foot].

The results of prostaglandin E1 et systemic antibacterial therapy use in 1836 patients, suffering purulent-necrotic affection of foot, were summarized. There was established, that cefuroxym constitutes the first line preparation for the ostheoarthropathy focus elimination, when the affection is limited and the patient state is stable, and meronem--for extended affection and unstable patient's state. In the pronounced ischemia of the foot the initial administration of cefepim is the most effective. For purulent-necrotic affection as a consequence of the foot wounding, erysipelas or operative intervention it is expedient to use carbapenem or meropenem. The systemic antibacterial therapy administration had promoted significant reduction of the treatment duration and improvement of its result.

[Antibacterial therapy of purulent necrotic foot lesions in patients with diabetes mellitus]. / Antybakterial'na terapiia hniino-nekrotychnoho urazhennia stopy u khvorykh na tsukrovyi diabet.

Efficacy of antibacterial therapy was analyzed in 266 patients with diabetes mellitus and purulent-necrotic affection of the foot. In presence of affection of bones and joints good effect was achieved while conduction of antibacterial therapy and in the cases of open wound--while local administration of systemic antibacterial preparations.