ABSTRACT
BACKGROUND AND OBJECTIVES: The risk of sudden death and cardiac arrhythmia increases in morbidly obese patients. We aimed to evaluate the marker of arrhythmias such as Tp-e/QT, Tp-e/QTc, Tp-e/JT and Tp-e/JTc ratios in extreme obesity. METHODS: The study included 41 extremely obese patients and 41 control subjects. QTmax, QTmin, QRS, JT and Tp-e intervals were measured od 12lead electrocardiographies. In addition, Tp-e/QT, Tp-e/QTc, Tp-e/JT and Tp-e/JTc rates and QTc, cQTd and JTc intervals were calculated. RESULTS: Tp-e interval (79.2⯱â¯9.7â¯ms (milisecond) vs. 68.6⯱â¯8.1, pâ¯<â¯0.001), QTc interval (395.9⯱â¯18.8 vs. 377.9⯱â¯19.3â¯ms, pâ¯<â¯0.001), JTc interval (317.1⯱â¯27.0 vs. 297.4⯱â¯23.2â¯ms, pâ¯=â¯0.001), Tp-e/QT ratio (0.22⯱â¯0.03vs. 0.19⯱â¯0.02, pâ¯<â¯0.001), Tp-e/QTc ratio (0.20⯱â¯0.26vs. 0.18⯱â¯0.02, pâ¯=â¯0.001), Tp-e/JT ratio (0.29⯱â¯0.04 vs. 0.25⯱â¯0.03, pâ¯<â¯0.001), TPe/JTc ratio (0.25⯱â¯0.04 vs. 0.23⯱â¯0.03, pâ¯=â¯0.018), QTd (32.8⯱â¯10 vs.15⯱â¯6.4â¯ms, pâ¯<â¯0.001) and cQTd (70.0⯱â¯30.1 vs. 31.3⯱â¯22.4â¯ms, pâ¯<â¯0.001) were significantly higher in obese patients. CONCLUSION: Compared to healthy subjects potential ECG repolarization predictors were significantly increased in extremely obese patients.