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Biochemistry (Mosc) ; 64(10): 1196-9, 1999 Oct.
Article in English | MEDLINE | ID: mdl-10561568

ABSTRACT

Stability and catalytic properties of native and immobilized penicillin acylase were studied in systems with low water content. Preparations of both native and immobilized penicillin acylase demonstrated the catalytic activity even in solid-phase systems which contained 3-5 wt. % of water. The stability and catalytic activity of penicillin acylase at low water content depended on the thermodynamic water activity (aw) in the system.


Subject(s)
Penicillin Amidase/metabolism , Catalysis , Enzyme Stability , Enzymes, Immobilized/chemistry , Enzymes, Immobilized/metabolism , Penicillin Amidase/chemistry , Thermodynamics , Water/chemistry
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