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1.
Environ Geochem Health ; 42(11): 3675-3701, 2020 Nov.
Article in English | MEDLINE | ID: mdl-32488799

ABSTRACT

Groundwater is one of the most important sources of water for drinking and cooking in rural India. A total of 382 groundwater samples were collected from 58 villages and analyzed for HMs and Sr by inductively coupled plasma mass spectrometer. The average concentrations of HMs and Sr in water was in the order of strontium (Sr) > arsenic (As) > chromium (Cr) > lead (Pb) > mercury (Hg) > cadmium (Cd). Out of 58 villages, 21, 37, 35, 35, 35 and 39 villages had Cr, As, Cd, Hg, Pb and Sr higher (WHO limit) than their respectively permissible levels. Health risk assessment of HMs and Sr for humans revealed that the non-carcinogenicity hazard quotients (HQi+d) for HMs and Sr were higher than unity for adult and children. The hazard index (HI) was 531.066 for adult and 902.926 for children. The HI > 1 was observed in 45 villages for adults and 56 villages for children. The lifetime cancer risk in adult for Asi, Asd, and Pbi in 36, 25 and 23 villages, whereas in children was 42, 20 and 22 villages, respectively. In conclusion, the health risks arising from consumption of groundwater containing HMs and Sr indicated that there is a significant carcinogenic risks for adult and children. This is the first attempt to provide information on the health risks of Sr in drinking water in India. The present findings can be useful for the development of potential strategies for risk control and management.


Subject(s)
Dietary Exposure/adverse effects , Metals, Heavy/analysis , Strontium/analysis , Water Pollutants, Chemical/analysis , Water Pollutants, Chemical/toxicity , Adult , Carcinogens/analysis , Carcinogens/toxicity , Child , Cooking , Dietary Exposure/analysis , Drinking Water/analysis , Groundwater/chemistry , Humans , India , Metals, Heavy/toxicity , No-Observed-Adverse-Effect Level , Risk Assessment , Strontium/toxicity
2.
Int J Vitam Nutr Res ; 85(1-2): 14-22, 2015.
Article in English | MEDLINE | ID: mdl-26780273

ABSTRACT

Anemia among adolescent girls is one of the major challenges faced by India. The present study was undertaken to assess the prevalence of anemia and status of other hematological parameters among adolescent girls (11 - 18 years) residing in an urban slum of Delhi. A total of 794 adolescent girls were recruited for the study. The prevalence of anemia was estimated using the cyanmethemoglobin method. Serum levels of ferritin, folic acid and vitamin B12 were estimated for anemic subjects. The prevalence of anemia was reported as 58.7 %, with 31.6 %, 25.7 % and 1.4 % of subjects being mild, moderate and severely anemic. Hemoglobin levels of subjects who had attained menarche were found to be significantly lower than those who had not attained menarche. The prevalence of serum ferritin, folic acid and vitamin B12 deficiency among those who were anemic was reported as 41.1 %, 5.0 % and 63.3 % respectively. A total of 23.5 % anemic subjects had concomitant micronutrient deficiencies of serum vitamin B12 and ferritin. The results indicate that supplemental iron and vitamin B12 may better address the burden of anemia in adolescent girls in Delhi.


Subject(s)
Ferritins/deficiency , Folic Acid Deficiency/epidemiology , Poverty Areas , Vitamin B 12 Deficiency/epidemiology , Adolescent , Anemia/epidemiology , Anemia, Iron-Deficiency/epidemiology , Body Mass Index , Child , Female , Ferritins/blood , Hemoglobins/analysis , Humans , India/epidemiology , Micronutrients/deficiency , Nutritional Status , Urban Population
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