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1.
Ned Tijdschr Geneeskd ; 1662022 07 21.
Article in Dutch | MEDLINE | ID: mdl-36036698

ABSTRACT

In this article we provide an overview of the current treatment recommendations for COVID-19. These recommendations are made by the SWAB (StichtingWerkgroepAntibioticabeleid), in cooperation with the FMS (FederatieMedischSpecialisten (online: swab.nl/nl/covid-19.). Treatment options for patients in both ambulatory care and admitted to the hospital are listed. These treatment options include both antiinflammatory and antiviral therapy.


Subject(s)
COVID-19 , Hospitalization , Humans , Inpatients , SARS-CoV-2
2.
Ned Tijdschr Geneeskd ; 1642020 11 12.
Article in Dutch | MEDLINE | ID: mdl-33331727

ABSTRACT

Much has changed in the medical treatment of COVID-19 after the first patient with an infection with SARS-CoV-2 in the Netherlands was diagnosed in February 2020. On the basis of limited data, at first only off-label use of (hydroxy)chloroquine seemed to be a treatment option. However, now based on the findings of several randomized studies, other medicines have been included in the Dutch guidelines about the treatment of COVID-19. In this article, we will briefly discuss the current state of affairs with regard to the drugs (hydroxy) chloroquine, remdesivir and corticosteroids. Again, it appears that only well-executed randomized clinical trials can determine the status of various supposedly effective drugs.


Subject(s)
Adenosine Monophosphate/analogs & derivatives , Alanine/analogs & derivatives , COVID-19 Drug Treatment , COVID-19 , Drug Repositioning , Glucocorticoids , Hydroxychloroquine , SARS-CoV-2/drug effects , Adenosine Monophosphate/pharmacology , Adenosine Monophosphate/therapeutic use , Alanine/pharmacology , Alanine/therapeutic use , Anti-Inflammatory Agents/pharmacology , Anti-Inflammatory Agents/therapeutic use , Antiviral Agents/pharmacology , Antiviral Agents/therapeutic use , COVID-19/epidemiology , Drug Repositioning/methods , Drug Repositioning/standards , Glucocorticoids/pharmacology , Glucocorticoids/therapeutic use , Humans , Hydroxychloroquine/pharmacology , Hydroxychloroquine/therapeutic use , Netherlands/epidemiology , Randomized Controlled Trials as Topic , Treatment Outcome
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