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1.
Respiration ; 93(6): 436-440, 2017.
Article in English | MEDLINE | ID: mdl-28355597

ABSTRACT

Treatment options for intractable life-threatening haemoptysis in mechanically ventilated patients with structural lung disease who do not respond to bronchial artery embolisation (BAE) and who are deemed unfit for surgery are limited. A 26-year-old HIV-positive male with a poorly preserved CD4 count and active pulmonary tuberculosis was intubated and mechanically ventilated for persistent life-threatening haemoptysis. Two attempts at BAE failed, and life-threatening haemoptysis recurred daily for 14 days despite antituberculous therapy. He was deemed unfit for surgery during that period. We proceeded to identify the source of bleeding endoscopically and implanted an endobronchial valve in the left upper lobe bronchus. Following the collapse of the affected lobe, haemoptysis ceased and the patient was promptly liberated from mechanical ventilation. He remained haemoptysis free for the duration of his hospitalisation. Endobronchial valves, therefore, may be a viable option in patients mechanically ventilated with persistent life-threatening haemoptysis in whom all other conventional measures fail and who are considered unfit for surgery.


Subject(s)
Hemoptysis/surgery , Prostheses and Implants , Salvage Therapy , Shock, Hemorrhagic/surgery , Adult , Antitubercular Agents/therapeutic use , Bronchoscopy , HIV Infections/complications , Hemoptysis/complications , Hemoptysis/diagnostic imaging , Humans , Male , Radiography, Thoracic , Respiration, Artificial , Shock, Hemorrhagic/etiology , Suction , Tuberculosis, Pulmonary/complications , Tuberculosis, Pulmonary/diagnostic imaging , Tuberculosis, Pulmonary/therapy
2.
Respiration ; 92(6): 428-431, 2016.
Article in English | MEDLINE | ID: mdl-27760430

ABSTRACT

A 66-year-old female from a rural area in South Africa presented with non-life-threatening haemoptysis. Radiologic and serological investigations attributed her symptoms to bilateral, large echinococcal cysts. She declined surgery despite her lung physiologic parameters, which deemed her eligible. Medical therapy with oral albendazole was initiated with excellent clinical and radiologic response during a follow-up period of 18 months. To our knowledge, this is one of the first reported cases in the literature that shows complete resolution of bilateral large echinococcal cysts with medical treatment alone in an adult patient.


Subject(s)
Albendazole/therapeutic use , Anthelmintics/therapeutic use , Echinococcosis, Pulmonary/drug therapy , Aged , Echinococcosis, Pulmonary/diagnostic imaging , Female , Humans , Radiography, Thoracic , Tomography, X-Ray Computed , Treatment Outcome
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