ABSTRACT
The aim of the study was to evaluate the peculiarities of local left and right ventricular myocardial contractility in patients with coronary heart disease (CHD) and various degrees of chronic heart failure (CHF) using biventricular radioventriculography (RVG). Local left and right ventricular myocardial contractility was evaluated in 127 patients with CHD and CHF using RVG with a standard procedure of segmentary and phase histogram analysis. The patients were divided into two groups according to left ventricular ejection fraction (LVEF). Group I consisted of 89 CHD patients with NYHA II-III CHF and LVEF of > 40%; group II included 38 CHD patients with NYHA III-IV CHF and LVEF of < 40%. The significant decrease of LVEF in group II was caused by the prevalence of hypo- and akinetic segments in the structure of local contractility. In both groups total LVEF was maintained by lateral wall segments. Right ventricular contractility in patients with CHD and CHF was maintained by anteroseptal segments.
Subject(s)
Coronary Disease/physiopathology , Heart Failure/physiopathology , Myocardial Contraction , Aged , Coronary Disease/diagnostic imaging , Female , Heart Failure/diagnostic imaging , Humans , Male , Middle Aged , Myocardial Contraction/physiology , Radionuclide Ventriculography , Stroke Volume , Ventricular Function, Left , Ventricular Function, RightABSTRACT
A case is reported illustrating relationship between marked coronary atherosclerosis with development of painless myocardial ischemia (PMI) and constantly recurrent paroxysms of cardiac fibrillation (CF). A male 62-year-old patient suffering from paroxysmal CF received cordaron in a dose 200 mg twice a day. The treatment was ineffective until a comprehensive examination (thyroid hormones, echocardiography, Holter ECG monitoring, treadmill test, CT of the coronary arteries) found PMI episodes and severe stenosing atherosclerosis and the treatment was changed for sotalex (80 mg twice a day). Sotalex treatment was effective and stopped recurrences of CF.
Subject(s)
Myocardial Ischemia/diagnosis , Tachycardia, Paroxysmal/diagnosis , Coronary Artery Disease/complications , Humans , Male , Middle Aged , Myocardial Ischemia/complications , Myocardial Ischemia/drug therapy , Myocardial Ischemia/pathology , Recurrence , Risk Factors , Tachycardia, Paroxysmal/drug therapy , Tachycardia, Paroxysmal/etiology , Tachycardia, Paroxysmal/pathology , Treatment OutcomeABSTRACT
The aim of the study was to assess prestarium effects on systolic and diastolic cardiac functions in 38 patients with ischemic heart disease and chronic cardiac failure (NYHA functional class II-IV) by biventricular balanced radioventriculography. Both left and right ventricular diastolic dysfunction was found. A course of prestarium treatment caused different alterations in ventricular contractility. 64.2% patients of those who had right ventricular ejection fraction < 40% achieved an increase in right and left ventricular ejection fraction. Improved diastolic function of the myocardium was registered in 71% patients.
