ABSTRACT
Several glycosides were isolated, as polyacetates, from the n-BuOH fraction of the Tinospora cordifolia stems. The structures of three new norditerpene furan glycosides cordifoliside A, B and C have been established by 1D and 2D NMR spectroscopy.
Subject(s)
Diterpenes/isolation & purification , Glycosides/isolation & purification , Plants, Medicinal/chemistry , Carbohydrate Conformation , Carbohydrate Sequence , Chromatography, Thin Layer , Diterpenes/chemistry , Furans , Glycosides/chemistry , India , Magnetic Resonance Spectroscopy , Molecular Sequence DataABSTRACT
The saliva of habitual chewers of tobacco and of non- chewers was examined using high-performance liquid chromatography and gas-liquid chromatography-thermal energy analysis. N-Nitrosodimethylamine, N-nitrosodiethylamine, N-nitrosopyrrolidine, N-nitrosonornicotine and N- nitrosohydroxyproline were detected in the saliva from the tobacco chewers . These N-nitroso compounds are probably leached from the tobacco itself and/or are formed in situ by the nitrosation of tobacco alkaloids as well as that of secondary amines. No N-nitroso compounds were detected in the saliva of non- chewers .