Maternal periodontal disease and preterm or extreme preterm birth: an ordinal logistic regression analysis.

BACKGROUND: Despite previous studies addressing the link between preterm or low birth weight infants and maternal periodontitis, extreme preterm births have received far less attention. This study is designed to address the possible association between maternal periodontal disease and preterm or extreme preterm birth. METHODS: Immediately after childbirth, 1,207 women underwent an examination in which periodontal disease was assessed according to two alternative definitions: 1) four or more teeth with at least one site showing probing depth (PD) >or=4 mm and clinical attachment loss (AL) >or=3 mm, and 2) at least one site showing PD and clinical AL >or=4 mm. For each of these definitions, two types of multivariate analysis were conducted: a linear regression analysis for the number of gestation weeks, and a more specific ordinal logistic regression analysis for the ordinal variable gestation time categorized as normal (term) (n = 1,046 women) or mild-moderate (n = 146 women) or extreme preterm (n = 15 women). RESULTS: Periodontal disease was associated with fewer weeks of gestation by linear regression (definition 1: P = 0.012; definition 2: P <0.001) and with preterm (n = 161; mild-moderate and extreme) or extreme preterm births (n = 15) by ordinal logistic regression (definition 1: odds ratio [OR] = 1.83, 95% confidence interval [CI]: 1.28 to 2.62; definition 2: OR = 2.37, 95% CI: 1.62 to 3.46). CONCLUSION: Our findings suggest that periodontal disease is associated with a premature or extremely premature birth.

Maternal periodontitis as a potential risk variable for preeclampsia: a case-control study.

BACKGROUND: Association studies between maternal periodontitis and an elevated risk for preeclampsia have shown conflicting results. The aims of the present case-control study were: 1) to evaluate the association between maternal periodontitis and preeclampsia before and after matching, assessing confounding and interaction; and 2) to evaluate the influence of the extent and severity of periodontal parameters, bleeding on probing (BOP), probing depth (PD), and clinical attachment loss (CAL), in association with preeclampsia. METHODS: Initially, 1,206 Brazilian women were included and divided into a control group (1,042 non-preeclamptic women who gave birth to infants with adequate gestational age and birth weight) and a case group (164 preeclamptic women). Further, 125 preeclamptic women were matched according to age, chronic hypertension, and primiparity to 375 non-preeclamptic women randomly selected from the control group. Maternal periodontitis was defined as PD > or =4 mm and CAL > or =3 mm at the same site in at least four teeth. The effect of variables of interest and confounding were assessed by univariate and multivariate analysis. RESULTS: After controlling for confounders, maternal periodontitis was included in the multivariate final model (odds ratio [OR] = 1.94; 95% confidence interval [CI]: 1.37 to 2.77; P <0.001) and remained associated with preeclampsia after matching (OR = 1.52; 95% CI: 1.01 to 2.29; P = 0.045). The odds of preeclampsia were associated with an increase in the number of sites with BOP and PD and CAL > or =4 mm. CONCLUSION: Maternal periodontitis is a risk factor associated with preeclampsia, emphasizing the importance of periodontal care in prenatal programs.

Intrauterine growth restriction, low birth weight, and preterm birth: adverse pregnancy outcomes and their association with maternal periodontitis.

BACKGROUND: It has been suggested that periodontitis is associated with systemic alterations such as adverse pregnancy outcomes. However, some conflicting results have been reported. This case-control study was conducted to determine the association between maternal periodontitis and preterm birth (PTB), low birth weight (LBW), and intrauterine growth restriction (IUGR). METHODS: A total of 1,305 Brazilian women from multiethnic groups were enrolled and divided into four groups: control group (1,042 women who gave birth to infants with adequate gestational age and birth weight); PTB group (238 women, gestational age <37 complete weeks); LBW group (235 women, birth weight <2,500 g); and IUGR group (77 women who gave birth to infants with fetal growth retardation). Periodontitis was defined as the presence of at least four teeth with one or more sites with probing depth > or =4 mm and clinical attachment loss > or =3 mm. The effects of variables of interest, confounders, and interaction were tested through univariate and multivariate logistic regression tests. RESULTS: After adjusting for variables of interest, maternal periodontitis was retained in the final model for PTB (odds ratio [OR] = 1.77; 95% confidence interval [CI]: 1.12 to 2.59), LBW (OR = 1.67; 95% CI: 1.11 to 2.51), and IUGR (OR = 2.06; 95% CI: 1.07 to 4.19). When the interaction between periodontitis and previous PTB was tested, an OR of 5.94 (P <0.001), 9.12 (P <0.001), and 18.90 (P <0.001) was observed for PTB, LBW, and IUGR, respectively. CONCLUSIONS: Maternal periodontitis is associated with an increased risk for PTB, LBW, and IUGR. Results emphasize the importance of periodontal care in prenatal health programs.

Oral metastasis of breast carcinoma diagnosed by fine needle aspiration cytology. A case report.

BACKGROUND: Fine needle aspiration cytology (FNAC) is an important technique in the diagnosis of oral and maxillofacial conditions. The purpose of the present paper is to report a case of oral metastasis of breast carcinoma diagnosed by FNAC. CASE: A 45-year-old, black woman was referred for evaluation of symptomatic swelling in the left mandible. The medical history revealed that the patient had undergone extensive surgery to remove a lobular carcinoma. She had finished chemotherapy treatment about 5 months earlier. Due to the main diagnostic considerations of metastatic and inflammatory disease, FNAC was performed. The cytologic picture was consistent with a metastatic glandular neoplasm. CONCLUSION: FNAC is a safe, reliable, cost-effective and easy procedure and sometimes eliminates the need for open biopsy.

Restauração de dilaceração coronária e hipoplasia do esmalte / Restoration of crown dilaceration and enamel hypoplasia

Os traumatismos dos dentes decíduos resultam, na maioria das vezes, de acidentes caseiros, e na maioria dos casos afetam os incisivos centrais superiores. Os incisivos decíduos são altamente suscetíveis às luxações, sendo que 4,4 a 22 por cento delas são luxações intrusivas. Este tipo de trauma pode resultar em danos tanto para o decíduo quanto para o germe do permanente, que apresentam vários tipos de anomalias de desenvolvimento. Andreasen et al. (1971) relataram que, após trauma dos dentes decíduos, quase 50 por cento dos permanentes sucessores mostraram distúrbios nos diferentes estágios da odontogênese. A paciente citada neste relato de caso apresentava os dentes 31 e 41 com dilaceração coronária associada à descoloração branco-amarelada do esmalte. A descoloração é devida a um distúrbio interno da mineralização, acarretando hipoplasia e hipocalcificação. A dilaceração constutui-se de uma angulação aguda no longo eixo da coroa. Mesmo sem a presença de lesões cariosas, dentes dilacerados podem tardiamente desenvolver necrose pulpar seguida de periodontite apical e abcesso crônico. Para evitar essa complicação, a parte dilacerada da coroa foi removida e os dentes foram devidamente tratados. A estética e a anatomia funcional foram restabelecidas através de restauração em resina composta fotopolimerizada, associada a pino de fibra de vidro intra-radicular. Essa técnica apresenta como vantagens a simplicidade de execução, o baixo custo e a possibilidade de ser realizada em uma única sessão, além do excelente resultado estético-funcional