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Carbapenemase-Producing Enterobacteriaceae and Nonfermentative Bacteria, the Philippines, 2013-2016.

Velasco, John Mark; Valderama, Maria Theresa; Peacock, Trent; Warawadee, Nirdnoy; Nogrado, Kathyleen; Navarro, Fatima Claire; Chua, Domingo; Apichai, Srijan; Sirigade, Ruekit; Macareo, Louis R; Swierczewski, Brett.

Emerg Infect Dis ; 23(9): 1597-1598, 2017 09.

Article in English | MEDLINE | ID: mdl-28820383

ABSTRACT

During 2013-2016, we isolated blaNDM- and blaVIM-harboring Enterobacteriaceae and nonfermentative bacteria from patients in the Philippines. Of 130 carbapenem-resistant isolates tested, 45 were Carba NP-positive; 43 harbored blaNDM, and 2 harbored blaVIM. Multidrug-resistant microbial pathogen surveillance and antimicrobial drug stewardship are needed to prevent further spread of New Delhi metallo-ß-lactamase variants.

Subject(s)

Bacterial Proteins/genetics , Carbapenem-Resistant Enterobacteriaceae/genetics , Enterobacteriaceae Infections/epidemiology , Plasmids/metabolism , beta-Lactam Resistance/genetics , beta-Lactamases/genetics , Anti-Bacterial Agents/pharmacology , Bacterial Proteins/metabolism , Carbapenem-Resistant Enterobacteriaceae/drug effects , Carbapenem-Resistant Enterobacteriaceae/isolation & purification , Carbapenems/pharmacology , Enterobacteriaceae Infections/drug therapy , Enterobacteriaceae Infections/microbiology , Gene Expression , Humans , Isoenzymes/genetics , Isoenzymes/metabolism , Microbial Sensitivity Tests , Multilocus Sequence Typing , Philippines/epidemiology , Plasmids/chemistry , Prevalence , Tertiary Care Centers , beta-Lactamases/metabolism

ABSTRACT

Subject(s)

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