ABSTRACT
Three years' data were analysed to assess the risk factors for neonatal Klebsiella septicemia in Srinagarind Hospital. The incidence of Klebsiella septicemia was 4.1 per 1,000 livebirths or 5.2 per 100 discharged infants. Eighty-two per cent of infected cases were low birth weight infants and 67.7% were born prematurely. From multivariate analysis, the risk factors were endotracheal intubation (OR 31.57, 95% CI 289-343.82) and central venous catheterization (OR 16.99, 95% CI1.15-250.37). The overall mortality rate was 67.7%. Periodic review and continuous reinforcement of infection control policies in the neonatal unit are of paramount importance to decrease the incidence of nosocomial infection and successful control of outbreaks as well.
Subject(s)
Bacteremia/transmission , Cross Infection/transmission , Developing Countries , Infant, Premature, Diseases/epidemiology , Klebsiella Infections/transmission , Bacteremia/prevention & control , Case-Control Studies , Cross Infection/prevention & control , Female , Humans , Infant, Low Birth Weight , Infant, Newborn , Infant, Premature, Diseases/prevention & control , Intensive Care Units, Neonatal/statistics & numerical data , Klebsiella Infections/prevention & control , Male , Retrospective Studies , Risk Factors , Thailand/epidemiologyABSTRACT
Surveillance of nosocomial infections (N.I.) in Srinagarind hospital was done from June 1987 to May 1988. Seven thousand three hundred and fifty-five discharged patients in 10 high risk wards were studied. Eight hundred and fourteen patients had N.I., and incidence rate of 11.06 per cent. There were 1,255 episodes of N.I., an infection rate of 17 per cent. Urinary tract infection was the commonest infection followed by lower respiratory infections. The infection rate was highest in the rehabilitation ward where patients were hospitalized longer than patients in other wards. The commonest pathogens isolated were P. aeruginosa, Klebsiella species and E. coli. Urinary tract infection was most common due to E. coli, while lower respiratory, bacteraemia, and both surgical wound, skin and soft tissue infections were due to P. aeruginosa, Klebsiella species and P. aeruginosa, respectively.