Subject(s)
Calcinosis/diagnostic imaging , Cardiomyopathy, Hypertrophic/diagnostic imaging , Coronary Angiography , Pericarditis, Constrictive/diagnostic imaging , Pericardium/diagnostic imaging , Tuberculosis, Cardiovascular/diagnostic imaging , Calcinosis/complications , Calcinosis/surgery , Cardiomyopathy, Hypertrophic/complications , Cardiomyopathy, Hypertrophic/surgery , Humans , Male , Middle Aged , Pericardiectomy , Pericarditis, Constrictive/complications , Pericarditis, Constrictive/surgery , Pericardium/surgery , Predictive Value of Tests , Tuberculosis, Cardiovascular/complications , Tuberculosis, Cardiovascular/surgeryABSTRACT
Hemolysis related to occluder, prosthetic valve, and prosthetic ring used for mitral valve annuloplasty are not very unusual. However, hemolysis related to transcathetor closure of post-myocardial infarction ventricular septal defect (PMIVSD) is infrequent. A close follow-up for spontaneous resolution with or without blood transfusion has been reported in a few cases. Occasionally, surgical retrieval is unavoidable or lifelong blood transfusion is required if surgery cannot be done because of higher risk. In this illustration, we have showed a close follow-up of a case of hemolysis induced by atrial septal occluder used for VSD closure after myocardial infarction. Despite successful device closure of PMIVSD which is difficult, a close watch is needed for complications like residual leak, device embolization, and hemolysis.
Subject(s)
Cardiac Surgical Procedures/adverse effects , Heart Septal Defects, Ventricular/surgery , Hemolysis , Postoperative Complications , Septal Occluder Device/adverse effects , Cardiac Catheterization , Electrocardiography , Follow-Up Studies , Heart Septal Defects, Ventricular/diagnosis , Heart Septal Defects, Ventricular/etiology , Humans , Male , Middle Aged , Myocardial Infarction/complications , Time FactorsABSTRACT
Alzheimer's disease and type 2 diabetes mellitus tend to occur together. We sought to identify protein(s) common to both conditions that could suggest a possible unifying pathogenic role. Using human neuronal butyrylcholinesterase (AAH08396.1) as the reference protein we used BLAST Tool for protein to protein comparison in humans. We found three groups of sequences among a series of 12, with an E-value between 0-12, common to both Alzheimer's disease and diabetes: butyrylcholinesterase precursor K allele (NP_000046.1), acetylcholinesterase isoform E4-E6 precursor (NP_000656.1), and apoptosis-related acetylcholinesterase (1B41|A). Butyrylcholinesterase and acetylcholinesterase related proteins were found common to both Alzheimer's disease and diabetes; they may play an etiological role via influencing insulin resistance and lipid metabolism.
