The distribution and transmission of Actinobacillus actinomycetemcomitans in families with localized juvenile periodontitis / Distribuição e transmissão de Actonobacillus actinomycetemcomitans em familias com periodontite juvenil localizada

The prevalence and distribution of A actinomycetemcomitans in families where at least one family member (proband) suffered from localized juvenile periodontitis was investigated. 25 probands with localized juvenile periodontitis (LJP) and their 78 close family members screened for the presence of A. actinomycetemcomitans. Among these 25 families, 10 contained at least one aditional family member colonized with oral A. actinomycetemcomitans. Genomic DNA from subgingival A. actinomycetemcomitans strains from each of the prob-ands and their family members were amplified and characterized by the polymerase chain reaction (PCR) using a single primer known do distinguish A. actinomycetemcomitans strains. The PCR products from ...