Blockchain and IoT Technology in Healthcare: A Review.

The tremendous shift in technology has led to many unconnected things getting interconnected via IoT. IoT is one of the major modes of collecting data from various networked resources and other connected devices. The broad range of IoT, with its huge heterogeneity in handling data, addresses many challenges in the realm of healthcare. Blockchain technology has elevated the use of distributed storage in a positive way. The recent emergence of this technology has paved way for potentially enormous utilization in various fields. Blockchain technology in the fields of IT, finance, industries, government, healthcare, media, and law enforcement has altered the service quality levels to an ethical ideal. Blockchain, in conjunction with IoT, facilitates decentralized collection and storage of data. Integrating blockchain with IoT has emerged as a cutting-edge tool for the decentralized sharing of medical records, monitoring of patients, ensuring the privacy of patient records, predicting the quantum of insurance, and managing supply chains.

Comparative toxicity studies in birds using nimesulide and diclofenac sodium.

Nimesulide, a sulfonanilide derivative, was compared with diclofenac sodium for toxicity in poultry. In this study, Vanaraja and PB1 birds of 6 weeks old (either sex) were mixed and equally divided into 5 groups of 10 birds each. The birds were inoculated with nimesulide, @ 5 and 2mg; vehicle @ 0.5ml; and diclofenac sodium @ 5mg on kg bwt basis. One group served as untreated control. All the groups were observed for a period of 28days. Forty percent mortality was observed within 12 days in diclofenac-treated group. While birds inoculated with nimesulide remained normal. No significant differences in the weight gain, haematology, total protein contents in the nimesulide and diclofenac groups (survived birds) were observed when compared with the control group of birds. Serum creatinine, cholesterol, alkaline phosphatase, and aspartate aminotransferase levels were significantly (P<0.05) high in diclofenac-treated group compared to nimesulide (P>0.05) and control groups. Nimesulide-treated groups did not show any histopathological lesions, where as diclofenac-treated birds showed histopathological lesions in liver and kidney.