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Farmaco Sci ; 37(4): 266-74, 1982 Apr.
Article in English | MEDLINE | ID: mdl-7084448

ABSTRACT

Condensation of dimethyl 2-chloro-6-methylpyridine-3,4-dicarboxylate with thiourea and its N-substituted derivatives is described. It has been found that depending on the kind of substituents in the starting thiourea derivatives, pyrido [3,2-e]-1,3-thiazine or pyrido [2,3-d] pyrimidine derivatives were formed.


Subject(s)
Serotonin Antagonists/chemical synthesis , Thiazines/chemical synthesis , Animals , Anti-Inflammatory Agents/chemical synthesis , Anticonvulsants/chemical synthesis , Chemical Phenomena , Chemistry , Hexobarbital/pharmacology , Lethal Dose 50 , Mice , Rats , Reserpine/antagonists & inhibitors , Sleep/drug effects , Thiazines/pharmacology
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