ABSTRACT
OBJECTIVES: The aim of this study was to assess the prevalence, incidence and the burden of rheumatoid arthritis (RA) in the Southern Albania. MATERIAL AND METHODS: This is an epidemiologic observational study with cross-sectional analyses of all patients with RA who lived in Southern Albania during the 1995-2011 years. The RA prevalence, incidence and disability-adjusted life years (DALY) were assessed. RESULTS: During the 1995-2011 years, 194 patients (154 females and 40 males) with RA living in Southern Albania were identified. The prevalence of RA in 2011 was 0.25% in general population and 0.34% in adult (>14 years) population. The incidence of RA in 2011 was 0.012% (12 new cases per 100000 inhabitants) and 0.016% (16 new cases per 100000 adults). The prevalence increased (from 0.036% in 1996 to 0.25% in 2011) and the incidence did not change over the study period. The mortality was 3.2% (n=7 deaths). The DALY due to RA was 823 years per 100000 inhabitants during 1995-2011 years. CONCLUSION: RA in Southern Albania has a prevalence of 0.25 % and an annual incidence of 0.012% in the general population in 2011. RA was responsible for a considerable burden on the health of population during the 1995-2011 years.
ABSTRACT
OBJECTIVES: To evaluate the incidence and prevalence of ankylosing spondylitis (AS) in southern Albania and to assess the association of various demographic risk factors with the severity of disease. MATERIAL AND METHODS: This is an observational study with cross-sectional analyses, conducted in the region of Gjirokaster, between 1995 until 2011. The diagnosis of AS was based on the modified New York criteria. Data on population are obtained from the reports of the National Institute of Statistics. RESULTS: Between 1995 and 2011, there were 54 patients diagnosed with AS. Of them, 48 subjects were males (88.9%) and 6 subjects females (11.1%). The AS prevalence in adult population (≥14 years of age), in December 2010, was 0.061%. The 5-year incidence (2006-2010) in adult population was 0.006 %. The mean age at the onset of disease was 29.7±8.4 years. The mean age in 2011 (n=50 subjects) was 51.6±12.7 years. The duration of the disease was 22.7±11.2 years. More than two thirds of the patients (70.3%) were in the advanced radiological stages of the disease. A younger age at the onset of the disease, longer delay in diagnosis, lower educational level and smoking were significant independent factors associated with the advanced forms of the disease. CONCLUSION: In southern Albania, the AS prevalence in 2010 was 0.061% and the 5-year incidence (2006-2010) was 6 new cases per 105 adults. The incidence and prevalence of AS in Southern Albania are close to the respective regional epidemiological data.
ABSTRACT
INTRODUCTION: Biochemical and physiological mechanisms by which lead affects the cardiovascular system by increasing blood pressure are still unknown. But it is believed that the increased arterial pressure disturbance is caused as a result of the concentration of intracellular calcium ions (Ca). AIM OF THE STUDY: The study had the purposes of analyzing the effect of lead in blood pressure at the mine workers in "Trepca" Stan Terg comparing years worked in the mine. MATERIAL AND METHODS: The study included 55 workers at Stan Terg Trepca mine, out of which 44 are direct employees who work within the galleries of the mine and 11 workers outside the galleries of the mine, The Control Group. RESULTS: From the data provided in the study, it is noted an increase of arterial blood pressure value (Systolic and Diastolic) at workers who have worked directly in the mine gallery in comparison with The Control Group. DISCUSSION: Workers with the longest time worked in the mine have the most pronounced increase of arterial blood pressure values than those with less working experience. Lead affects the blood pressure and is closely dependent on the workplace and the years worked in the mine. CONCLUSION: Protective measures are necessary in prevention of lead poisoning in the workplace.
