[The experience with the application of a lyophilized xenodermograft for the treatment of the patients suffering from frequently recurring inflammation of the maxillary sinus in combination with alveolar fistula].

The objective of the present study was to summarize the data of the special literature concerning methods of the surgical treatment of odontogenic maxillary sinusitis complicated by the alveolar fistula with the purpose of using them for the improvement of the effectiveness of the treatment of the patients presenting with this pathology. The study group was comprised of 39 patients with odontogenic diseases of paranasal sinuses and alveolar fistulas. The alveolar fistulas were closed in 20 patients by means of plastic surgery with the use of a lyophilized xenodermograft prepared from the pig's skin. Not a single case of relapse of the inflammatory process in the maxillary sinuseswas documented within one year after the treatment by means of the closure of the alveolar fistula using the lyophilizedxenodermografts.

[Activation of lipid peroxides in the liver during hypokinesia and its prevention by antioxidants]. / Aktivatsiia perekisnogo okisleniia lipidov v pecheni pri gipokinezii i preduprezhdenie ee antioksidantami.

Experiments on white rats showed that exposure to hypokinesia increased peroxidation of unsaturated fatty acids of lipids of cell membranes, decreased the content of sulfhydryl groups, and increased the content of disulphide groups. This was very marked during the first 4-7 days, i.e., during the time of a distinct stress-reaction. At later stages the rate of free radical processes decreased slightly. In the recovery period that followed 7-day hypokinesia lipid peroxidation in the rats gradually returned to normal. The initiation of free radical reactions during hypokinesia can be prevented by means of antioxidants (acetate tocopherol, sodium selenite) and syrepar.

[Bile-forming function of the liver in the white rat]. / Zhelcheobrazovatel'naia funktsiia pecheni u belykh krys.

White male rats were exposed to hypokinesia of 4 to 30 days in duration. The exposure led to a moderate hypersecretion of gall which was more distinct in autumn and winter. The synthesis and secretion of gallic acid increased. The excretion of cholesterol also grew. The ratio of tauro- and glycoacids shifted in favor of the latter. The cholate cholesterol coefficient increased. These changes in gall formation during hypokinesia are closely related to disorders in lipid and carbohydrate metabolism, as well as in adrenal function.

[The effect of syrepar and oxaphenamide on liver function in experimental hypokinesia]. / Vliianie sirepara i oksafenamida na funktsional'noe sostoianie pecheni pri eksperimental'noi gipokinezii.

Experiments set up on albino rats evidenced that 30-day hypokinesia changes the reaction of the liver to cholagogues. In particular, the degree of the choleretic action of oxaphenamide as well as of its inhibitory affect on the synthesis of bile acids diminshes, while the influence on the bilirubin secretion -- increases. In hypokinesia syreper, inhibits biliation, but stimulates the secretion of bilirubin. Owing to a reduced secretion of cholesterol the cholesterol-stablizing properties of the bile improve.

[Effectiveness of syrepar in experimental liver dystrophy in albino rats]. / Effektivnost' sirepara pri eksperimental'noi distrofii pecheni u belykh krys

In experiments with rats it was found that syrepar is an effective agent in acute dystrophy provoked by carbon tetrachloride. Its daily administration in an amount of 0.1 ml per 100 g of weight subcutaneously improves the general condition of the animals, prevents their destruction, accelerates restoration of the structure and function of the liver. Much earlier and more fully the cholepoietic function of the liver, the ultrastructural organization of hepatocytes, as well as the activity of hepatic enzymes, along with the glycogen content and of cytoplasmatic RNA were re-established.