ABSTRACT
What was the nature of the CPD activity, practice-related feedback and/or event and/or experience in your practice? The CPD article discussed the importance of human immunodeficiency virus (HIV) testing and diagnosing the condition as early as possible, so that antiretroviral treatment can be initiated and patient outcomes improved.
Subject(s)
Certification , HIV Infections/diagnosis , Education, Nursing, Continuing , Humans , United KingdomABSTRACT
Paracetamol is safe and effective at the therapeutic dose. It is beneficial as an analgesic and is an effective antipyretic. Paracetamol is cheap and easy to buy over the counter, which makes it a common choice in intentional overdose.
Subject(s)
Acetaminophen/poisoning , Poisoning/nursing , Poisoning/pathology , Analgesics/adverse effects , Drug Overdose/epidemiology , Humans , United KingdomABSTRACT
Depression is a common mental health disorder that impairs normal functioning, causes distress and has an adverse effect on an individual's quality of life.
Subject(s)
Depression/diagnosis , Depression/nursing , Depressive Disorder/diagnosis , Depressive Disorder/nursing , Nursing Care/standards , Nursing Staff/education , Practice Guidelines as Topic , Education, Nursing, Continuing , Humans , Surveys and QuestionnairesABSTRACT
While I was aware of the link between high serum cholesterol and cardiovascular disease, I was unaware of the mechanism of atheroma development. The CPD article discussed the role of low-density lipoprotein in the development of atherosclerosis, which I found very interesting.
Subject(s)
Atherosclerosis/drug therapy , Cardiovascular Diseases/drug therapy , Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use , Hyperlipidemias/drug therapy , Education, Nursing, Continuing , Humans , Hydroxymethylglutaryl-CoA Reductase Inhibitors/adverse effects , Risk Factors , United KingdomSubject(s)
Patient Education as Topic/methods , Surgical Stomas , Body Image , Humans , United KingdomABSTRACT
I gained experience of psychiatric assessment in previous roles when working in a secure psychiatric ward and within the prison service. Although I have often performed mental state assessments and assessments of suicidal intent as part of my work, I read the CPD article to refresh my knowledge in this area.
Subject(s)
Emergencies , Health Services Needs and Demand , Mental Disorders/therapy , Humans , Mental HealthABSTRACT
Dengue fever is a notifiable infectious disease in England because of its geographic expansion and the increase in the number of epidemics. The article highlighted the importance of informing overseas travellers of the risk of acquiring dengue fever and advising them on personal protective measures.
Subject(s)
Dengue/prevention & control , Travel , HumansABSTRACT
A novel conditional-lethal transgene system is defined in which a mutated influenza A virus ion-channel protein, which is permeable to monovalent cations, is lethal to cells on heterotypic expression and whose activity can be blocked by an antiviral drug (amantadine), is used to reversibly disrupt T-cell development. In vivo expression of the M2 ion channel, as a transgene under control of the T-cell specific p56(Lck) proximal promoter, resulted in total ablation of T-cell development with the accumulation of three distinct populations of early progenitor cells (CD44(+) CD25(-); CD44(+) CD25(+); CD44(+) CD25(hi)) in the thymic rudiment. In vitro development of transgenic fetal thymic progenitors to single-positive T cells could be rescued by antiviral drug treatment. Moreover, there was a radical reduction in B-cell lymphopoiesis, evident at the pre-B-cell stage, with a twofold increase of lymphoid cells 'in cycle' in transgenic bone marrow, indicative of major changes in haematopoietic homeostasis. This system may provide a generic protocol for conditional, lineage-specific cell ablation with available tissue-specific promoters for any eukaryotic developmental system, and provide a window on early T-cell development.
