ABSTRACT
Because the pattern-reversal visual evoked response (PVER) reflects the central retinal function, PVER results generally agree with those of psychophysical tests. The visual acuities (VAs) calculated from PVER recordings and Snellen acuity (SA) measurements were compared in 500 eyes (261 patients; ages 8 to 88 years; mean, 44.5 years). The best-corrected VA was measured using the ETDRS chart, and the PVER acuity was determined by the smallest check size that produced a definite PVER (critical check size). In 288 eyes with a critical check size of 10 min of arc, the SAs ranged from 20/15 to 20/800 (mean 20/38). In 68 eyes with a critical check size of 20 min, the SAs ranged from 20/15 to 20/800 (mean 20/97). In 70 eyes with a critical check size of 40 min, the SAs ranged from 20/20 to 20/1600 (mean 20/156). In 29 eyes with a critical check size of 80 min and 14 eyes with a critical check size of 160 min, the SAs ranged from 20/50 to 20/1600 (mean 20/312 and 20/398, respectively). In 31 eyes in which the PVER was non-recordable, the SAs ranged from 20/70 to 20/3200 (mean 20/1177). The PVER acuity using the smallest check size seemed to agree with the SA, but large deviations were observed in certain subjects.
Subject(s)
Evoked Potentials, Visual/physiology , Pattern Recognition, Visual/physiology , Visual Acuity/physiology , Adolescent , Adult , Aged , Aged, 80 and over , Child , Eye Diseases/physiopathology , Female , Humans , Male , Middle Aged , Retina/physiologyABSTRACT
A modification was made of the conventional method of recording the pattern reversal visual evoked response (VER) to study the VER in infants and young children. Application of this modified method to 36 patients, the majority of them with retinopathy of prematurity, showed that this method is useful in the evaluation of the visual function in infants and young children, and also in a 12-year-old mentally retarded girl.
Subject(s)
Evoked Potentials, Visual , Child , Child, Preschool , Diseases in Twins , Female , Humans , Infant , Infant, Newborn , Male , Ophthalmology/methods , Pattern Recognition, Visual , Vision Disorders/physiopathologyABSTRACT
Four cases of Laurence-Moon-Bardet-Biedl syndrome were studied through electrophysiological and psychophysical examinations, and findings were correlated with those of fluorescein angiography. In all cases the macula showed degenerative changes, including a bull's eye appearance. The fundus periphery could be devoid of clumps of pigmentation, but all cases showed profound functional abnormalities that affected the macula and the periphery, impairing both the cone and rod systems equally. Bull's eye macula associated with severe, diffuse functional abnormality of the macula and peripheral retina, along with obesity and mental retardation, help establish the diagnosis of Laurence-Moon-Bardet-Biedl syndrome.
